Evidence map›Paper›PMID 36281378›Full record

ArticleHeliyon2022

Quality control, preparation process optimizing and anti-inflammatory effects of

Kaiqi Liu, Yingying Guo, Xiaojing Chen, Jufeng Duan, Bei Li, Ming Liu, Lin Chen, Minglun Li, Yibin Feng, Hongliang Li and 1 more

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Molecules (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Kaiqi LiuSchool of Pharmaceutical Sciences; Laboratory of Chinese Herbal Pharmacology, Department of Pharmacy, Renmin Hospital; Biomedical Research Institute; Hubei Key Laboratory of Wudang Local Chinese Medicine Research; Hubei University of Medicine, 39 Middle Chaoyang Road, Shiyan, Hubei Province, 442000, China.
Yingying GuoSchool of Pharmaceutical Sciences; Laboratory of Chinese Herbal Pharmacology, Department of Pharmacy, Renmin Hospital; Biomedical Research Institute; Hubei Key Laboratory of Wudang Local Chinese Medicine Research; Hubei University of Medicine, 39 Middle Chaoyang Road, Shiyan, Hubei Province, 442000, China.
Xiaojing ChenSchool of Pharmaceutical Sciences; Laboratory of Chinese Herbal Pharmacology, Department of Pharmacy, Renmin Hospital; Biomedical Research Institute; Hubei Key Laboratory of Wudang Local Chinese Medicine Research; Hubei University of Medicine, 39 Middle Chaoyang Road, Shiyan, Hubei Province, 442000, China.
Jufeng DuanSchool of Pharmaceutical Sciences; Laboratory of Chinese Herbal Pharmacology, Department of Pharmacy, Renmin Hospital; Biomedical Research Institute; Hubei Key Laboratory of Wudang Local Chinese Medicine Research; Hubei University of Medicine, 39 Middle Chaoyang Road, Shiyan, Hubei Province, 442000, China.
Bei LiSchool of Pharmaceutical Sciences; Laboratory of Chinese Herbal Pharmacology, Department of Pharmacy, Renmin Hospital; Biomedical Research Institute; Hubei Key Laboratory of Wudang Local Chinese Medicine Research; Hubei University of Medicine, 39 Middle Chaoyang Road, Shiyan, Hubei Province, 442000, China.
Ming LiuSchool of Pharmaceutical Sciences; Laboratory of Chinese Herbal Pharmacology, Department of Pharmacy, Renmin Hospital; Biomedical Research Institute; Hubei Key Laboratory of Wudang Local Chinese Medicine Research; Hubei University of Medicine, 39 Middle Chaoyang Road, Shiyan, Hubei Province, 442000, China.
Lin ChenSchool of Pharmaceutical Sciences; Laboratory of Chinese Herbal Pharmacology, Department of Pharmacy, Renmin Hospital; Biomedical Research Institute; Hubei Key Laboratory of Wudang Local Chinese Medicine Research; Hubei University of Medicine, 39 Middle Chaoyang Road, Shiyan, Hubei Province, 442000, China.
Minglun LiDepartment of Radiation Oncology, University Hospital, LMU Munich, Marchioninistraße 15, 81377, Munich, Germany.
Yibin FengSchool of Chinese Medicine, The University of Hong Kong. Hong Kong, China.
Hongliang LiSchool of Pharmaceutical Sciences; Laboratory of Chinese Herbal Pharmacology, Department of Pharmacy, Renmin Hospital; Biomedical Research Institute; Hubei Key Laboratory of Wudang Local Chinese Medicine Research; Hubei University of Medicine, 39 Middle Chaoyang Road, Shiyan, Hubei Province, 442000, China.
Xuanbin WangSchool of Pharmaceutical Sciences; Laboratory of Chinese Herbal Pharmacology, Department of Pharmacy, Renmin Hospital; Biomedical Research Institute; Hubei Key Laboratory of Wudang Local Chinese Medicine Research; Hubei University of Medicine, 39 Middle Chaoyang Road, Shiyan, Hubei Province, 442000, China.
Hubei University of Medicine · CNChinese University of Hong Kong · HKLMU Klinikum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: The Results: Fifty-three compounds were initially identified in PP among which flavonoids were dominant (19 out of 53). The average values of water-soluble sugar content and total flavonoid content of PP were 13.366 and 4.970 mg/g, respectively. The best preparation process of PP was powder-liquid ratio 1: 20, temperature 90 °C, and stirring time 3 min. Data showed that PP reduced paw edema and decrease the serum level of IL-6, TNF-α and IL-1β in the model mice. There was no toxic effect of PP on mice at a total dose of 6000 mg/kg/24h. Conclusion: In summary, by optimizing the preparation process, PP with stable quality can be obtained. PP has anti-inflammatory effects without toxicity.

Indexed as

PectinPharmacological effectsPremna puberula ​Pamp.Preparation processQuality controlSafety assessment

Identifiers

PMID36281378
PMCPMC9587327
OpenAlexW4306175062

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.