Evidence map›Paper›PMID 36280834›Full record

ArticleBMC neurology2022

Non-invasive near-infrared spectroscopy assessment of the spinal neurovascular response in a patient with transverse myelitis: a case report.

Juan Esteban Oyarzún, Raúl Caulier-Cisterna, Juan Pablo González-Appelgren, Leticia Gonzalez, Oscar Trujillo, Antonio Eblen-Zajjur, Sergio Uribe

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Juan Esteban OyarzúnCentro de Imágenes Biomédicas, Pontificia Universidad Católica de Chile, Santiago, Chile.
Raúl Caulier-CisternaCentro de Imágenes Biomédicas, Pontificia Universidad Católica de Chile, Santiago, Chile.
Juan Pablo González-AppelgrenCentro de Imágenes Biomédicas, Pontificia Universidad Católica de Chile, Santiago, Chile.
Leticia GonzalezCentro de Imágenes Biomédicas, Pontificia Universidad Católica de Chile, Santiago, Chile.
Oscar TrujilloNeurology Department, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
Antonio Eblen-ZajjurLaboratorio de Neurociencia Traslacional, Facultad de Medicina, Universidad Diego Portales Santiago, Santiago, Chile.
Sergio UribeCentro de Imágenes Biomédicas, Pontificia Universidad Católica de Chile, Santiago, Chile. suribe@uc.cl.
Pontificia Universidad Católica de Chile · CLDiego Portales University · CL

Funding

COPEC-UC 2018R.1030Fondecyt 1181057FONDEF ID18I0064
6 · The paper itself

Abstract

backgroundTransverse myelitis (TM) is characterized by acute development of motor, sensory and autonomic dysfunctions due to horizontally diffused inflammation in one or more segments of the spinal cord in the absence of a compressive lesion. The not well-known inflammation process induces demyelination resulting in neurological dysfunction. CASE PRESENTATION: In this case report we used a functional Near-Infrared Spectroscopy (fNIRS) technique to evaluate changes in the peri-spinal vascular response induced by a peripheral median nerve electrical stimulation in a patient with chronic transverse myelitis (TM). fNIRS showed drastically reduced signal amplitude in the peri-spinal vascular response, compared to that obtained from a healthy control group throughout most of the C7-T1 and T10-L2 spinal cord segments.

conclusionThe potential use of this relatively non-invasive fNIRS technology support the potential clinical application of this method for functional test of the spinal cord through the assessment of the spinal neurovascular response.

Indexed as

Autonomic Nervous System DiseasesMyelitis, TransverseHumansInflammationSpectroscopy, Near-InfraredSpinal CordNear infrared spectroscopy (NIRS)Neuron-vascular couplingNon-invasive methodSpinal neuronal activitySpinal neurovascular responseTransverse myelitis

Identifiers

PMID36280834
PMCPMC9590209
OpenAlexW4307135004

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.