Evidence map›Paper›PMID 36280696›Full record

ArticleScientific reports2022

Feelings of loneliness, COVID-19-specific-health anxiety and depressive symptoms during the first COVID-19 wave in Swiss persons with multiple sclerosis.

Robert Hoepner, Stephanie Rodgers, Katharina Stegmayer, Nina Steinemann, Christina Haag, Pasquale Calabrese, Zina-Mary Manjaly, Anke Salmen, Jürg Kesselring, Chiara Zecca and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 1 country.

Robert Hoepner *Department of Neurology, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland.
Stephanie Rodgers *Epidemiology, Biostatistics and Prevention Institute, University of Zurich (UZH), Zürich, Switzerland.
Katharina Stegmayer *Translational Research Center, University Hospital of Psychiatry, University of Bern, Bern, Switzerland.
Nina SteinemannEpidemiology, Biostatistics and Prevention Institute, University of Zurich (UZH), Zürich, Switzerland.
Christina HaagEpidemiology, Biostatistics and Prevention Institute, University of Zurich (UZH), Zürich, Switzerland.
Pasquale CalabreseDivision of Molecular and Cognitive Neuroscience, University of Basel, Basel, Switzerland.
Zina-Mary ManjalyDepartment of Neurology, Schulthess Clinic, Zürich, Switzerland.
Anke SalmenDepartment of Neurology, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland.
Jürg KesselringDepartment of Neurology and Neurorehabilitation, Rehabilitation Centre Kliniken Valens, Valens, Switzerland.
Chiara ZeccaMultiple Sclerosis Center, Neurocenter of Southern Switzerland, EOC, Lugano, Switzerland.
Claudio GobbiMultiple Sclerosis Center, Neurocenter of Southern Switzerland, EOC, Lugano, Switzerland.
Milo A PuhanEpidemiology, Biostatistics and Prevention Institute, University of Zurich (UZH), Zürich, Switzerland.
Sebastian Walther *Translational Research Center, University Hospital of Psychiatry, University of Bern, Bern, Switzerland.
Viktor von Wyl *Epidemiology, Biostatistics and Prevention Institute, University of Zurich (UZH), Zürich, Switzerland. viktor.vonwyl@uzh.ch.
University of Zurich · CHUniversità della Svizzera italiana · CHUniversity Hospital of Bern · CHUniversity of Bern · CHETH Zurich · CHUniversity of Basel · CHValens Clinics · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of our study was to investigate whether self-reported feeling of loneliness (FoL) and COVID-19-specific health anxiety were associated with the presence of depressive symptoms during the first coronavirus disease 2019 (COVID-19) wave. Questionnaires of 603 persons of the Swiss Multiple Sclerosis Registry (SMSR) were cross-sectionally analyzed using descriptive and multivariable regression methods. The survey response rate was 63.9%. Depressive symptoms were assessed by the Beck Depression Inventory-Fast Screen (BDI-FS). COVID-19-specific health anxiety and FoL were measured using two 5-item Likert scaled pertinent questions. High scoring FoL (2.52, 95% confidence interval (CI) (2.06-2.98)) and/or COVID-19 specific health anxiety (1.36, 95% CI (0.87-1.85)) were significantly associated with depressive symptoms. Further stratification analysis showed that the impact of FoL on depressive symptoms affected all age groups. However, it was more pronounced in younger PwMS, whereas an impact of COVID-19 specific health anxiety on depressive symptoms was particularly observed in middle-aged PwMS. FoL and COVID-19-specific health anxiety were age-dependently associated with depressive symptoms during the first COVID-19 wave in Switzerland. Our findings could guide physicians, health authorities, and self-help groups to better accompany PwMS in times of public health crises.

Indexed as

COVID-19Multiple SclerosisAnxietyDepressionHumansLonelinessMiddle AgedSwitzerland

Identifiers

PMID36280696
PMCPMC9591317
OpenAlexW4307286197

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.