Evidence map›Paper›PMID 36280657›Full record

ArticleAdvances in experimental medicine and biology2023

Regulatory Mechanisms of Muscle Mass: The Critical Role of Resistance Training in Children and Adolescent.

F Castelli, M Valero-Breton, M Hernandez, F Guarda, J Cornejo, C Cabello-Verrugio, D Cabrera

Abstract read
PubMed Publisher
In one paragraph

Article in Advances in experimental medicine and biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Development of the Muscular and Skeletal System During Adolescence.Advances in experimental medicine and biology · 2026
    Review
  2. Association between Depressive Symptoms, Physical Activity, and Health Factors in Hispanic Emerging Adults.International journal of environmental research and public health · 2024
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

F CastelliExperimental Hepatology Laboratory, Department of Gastroenterology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
M Valero-BretonLaboratory of Muscle Pathology, Fragility and Aging, Faculty of Life Sciences, Universidad Andres Bello, Santiago, Chile.
M HernandezExperimental Hepatology Laboratory, Department of Gastroenterology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
F GuardaDepartmento de Endocrinología, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
J CornejoExperimental Hepatology Laboratory, Department of Gastroenterology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
C Cabello-VerrugioLaboratory of Muscle Pathology, Fragility and Aging, Faculty of Life Sciences, Universidad Andres Bello, Santiago, Chile. Claudio.cabello@unab.cl.
D CabreraExperimental Hepatology Laboratory, Department of Gastroenterology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile. dacabrer@uc.cl.
Pontificia Universidad Católica de Chile · CLUniversidad Andrés Bello · CLUniversidad de Santiago de Chile · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Muscle mass and strength are subjected to several regulations. We found endocrine signals such as growth hormone, insulin-like growth factor 1, testosterone, thyroid hormones, and glucocorticoids among them. Neural inputs also influence muscle development, modulating mass and strength. Among the external stimuli that modulate these muscular features is physical training such as resistance and endurance training. Specifically, resistance training can mediate an increase in muscle mass by hypertrophy in adults, but the effects in children and adolescents are full of myths for most of the population. However, the evidence shows that the impact of resistance training on children and adolescents is clear and provides a wide range of benefits. However, qualified professionals must be available since exercise prescription and subsequent supervision must follow this population's abilities, needs, and interests.

Indexed as

Resistance TrainingAdolescentAdultChildExerciseGlucocorticoidsHumansHypertrophyMuscle, SkeletalMuscle StrengthTestosteroneGlucocorticoidsTestosteroneAdolescentChildrenCortisolGlucocorticoidsGrowth hormoneHypertrophyMuscle massResistance trainingStrength

Identifiers

PMID36280657
OpenAlexW4307232720

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.