Evidence map›Paper›PMID 36280623›Full record

Observational studyAging clinical and experimental research2023

Geriatric syndromes and functions in older adults with COVID-19 hospitalized in sub-acute care: a multicenter study.

Alessandro Morandi, Neus Gual, Matteo Cesari, Miriam Mota, Valeria Buttò, Simona Gentile, Genny Balestreri, Alessandro Camussi, Caterina Platto, Thais Roig and 3 more

Open access · bronzeAbstract readObservational StudyMulticenter Study
In one paragraph

Observational study in Aging clinical and experimental research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 2 countries.

Alessandro MorandiAzienda Speciale Cremona Solidale, Via Zocco 21, 26100, Cremona, Italy. morandi.alessandro@gmail.com.ORCID http://orcid.org/0000-0003-4848-2507
Neus GualREFiT Bcn Research Group, Parc Sanitari Pere Virgili and Vall d'Hebrón Institut de Recerca (VHIR), Barcelona, Spain.
Matteo CesariIRCCS Istituti Clinici Scientifici Maugeri, Milan, Italy.
Miriam MotaREFiT Bcn Research Group, Parc Sanitari Pere Virgili and Vall d'Hebrón Institut de Recerca (VHIR), Barcelona, Spain.
Valeria ButtòAcute Geriatric Unit, San Gerardo Hospital, Monza, Italy.
Simona GentileAzienda Speciale Cremona Solidale, Via Zocco 21, 26100, Cremona, Italy.
Genny BalestreriGeriatric Clinic Unit, University-Hospital of Parma, Parma, Italy.
Alessandro CamussiGinecologia, Dipartimento Materno Infantile, ISSR Sa Raffaele, Milan, Italy.
Caterina PlattoDepartment of Internal Medicine, ASST Cremona, Cremona, Italy.
Thais RoigREFiT Bcn Research Group, Parc Sanitari Pere Virgili and Vall d'Hebrón Institut de Recerca (VHIR), Barcelona, Spain.
Ana M de AndrésREFiT Bcn Research Group, Parc Sanitari Pere Virgili and Vall d'Hebrón Institut de Recerca (VHIR), Barcelona, Spain.
Giuseppe BellelliAcute Geriatric Unit, San Gerardo Hospital, Monza, Italy.
Marco InzitariREFiT Bcn Research Group, Parc Sanitari Pere Virgili and Vall d'Hebrón Institut de Recerca (VHIR), Barcelona, Spain.
Vall d'Hebron Institut de Recerca · ESAzienda Ospedaliera San Gerardo · ITIstituti Ospitalieri di Cremona · ITUniversitat Oberta de Catalunya · ESUniversity of Milan · ITUniversity of Parma · ITVita-Salute San Raffaele University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAlternatives to conventional acute hospitalizations have been particularly useful during the COVID-19 pandemic. However, little is known on the management and outcomes of COVID-19 in older patient admitted to non-acute settings. The main aim of this study was to determine the effect of geriatrics syndromes on functional outcomes in older COVID-19 patients cared in sub-acute units.

methodsProspective multicenter observational cohort study of patients aged 65 years and older with COVID-19, admitted to sub-acute units in Italy and Spain. Multivariable logistic regression models were used to test the association between geriatric syndromes and other clinical variables, and the functional status at discharge, defined by a Barthel Index >  = 80.

resultsA total of 158 patients were included in the study with a median age of 82 [Interquartile Range 81, 83]; of these 102 (65%) patients had a Barthel Index ≥ 80 at discharge. In the main multivariable logistic regression model a higher severity of frailty-measured with the Clinical Frailty Scale-(OR 0.30; CI 0.18-0.47), and the presence of delirium (OR 0.04; CI 0.00-0.35) at admission were associated with lower odds of a higher functional status at discharge. Other variables associated with lower functional status were female gender (OR 0.36; CI 0.13-0.96), and a higher number of comorbidities (OR 0.48; CI 0.26-0.82).

conclusionThe study reports a relatively high prevalence of functional recovery for older COVID-19 patients admitted to sub-acute units. Additionally, it underlines the importance of targeting geriatrics syndromes, in particular frailty and delirium, for their possible effects on functional recovery.

Indexed as

COVID-19DeliriumFrailtyAgedFemaleFrail ElderlyGeriatric AssessmentHumansMalePandemicsProspective StudiesSubacute CareSyndromeCOVID-19DeliriumElderlyFrailtyPsychoactive drugs

Identifiers

PMID36280623
PMCPMC9591316
OpenAlexW4307297948

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.