Evidence map›Paper›PMID 36280392›Full record

ArticleAmerican journal of physiology. Cell physiology2022

Molecular regulation of stretch activation.

Joel C Robinett, Laurin M Hanft, Brandon Biesiadecki, Kerry S McDonald

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Cell physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Joel C RobinettDepartment of Medical Pharmacology and Physiology, School of Medicine, University of Missouri, Columbia, Missouri.
Laurin M HanftDepartment of Medical Pharmacology and Physiology, School of Medicine, University of Missouri, Columbia, Missouri.
Brandon BiesiadeckiDepartment of Physiology and Cell Biology, The Ohio State University, Columbus, Ohio.
Kerry S McDonaldDepartment of Medical Pharmacology and Physiology, School of Medicine, University of Missouri, Columbia, Missouri.ORCID 0000-0002-1588-1782
The Ohio State University · USUniversity of Missouri · US

Funding

Integrated Crosstalk of Thin Filament Post-translational ModificationsR01HL114940 · NHLBI · OHIO STATE UNIVERSITY · PI BIESIADECKI, BRANDON J · 2013 to 2021
$3.6M
Dual filament control of myocardial power and hemodynamicsR01HL148785 · NHLBI · UNIVERSITY OF MISSOURI-COLUMBIA · PI Kenneth S Campbell, Thomas Kampourakis · 2020 to 2026
$3.2M
NHLBI NIH HHS R01 HL114940NHLBI NIH HHS R01 HL148785
6 · The paper itself

Abstract

Stretch activation is defined as a delayed increase in force after rapid stretches. Although there is considerable evidence for stretch activation in isolated cardiac myofibrillar preparations, few studies have measured mechanisms of stretch activation in mammalian skeletal muscle fibers. We measured stretch activation following rapid step stretches [∼1%-4% sarcomere length (SL)] during submaximal Ca

Indexed as

CalciumMyofibrilsAnimalsCyclic AMP-Dependent Protein KinasesHumansMammalsMyocardial ContractionMyocardiumMyosinsPhosphorylationProtein-Tyrosine KinasesRatsSarcomeresTroponin ICalciumCyclic AMP-Dependent Protein KinasesMyosinsProtein-Tyrosine KinasesTroponin Imyosin binding protein-Cslow-twitch skeletal muscle fiberstretch activationtransient force overshoottroponin I

Identifiers

PMID36280392
PMCPMC9744651
OpenAlexW4307229329

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.