Evidence map›Paper›PMID 36280288›Full record

ArticleeNeuro

Chronic Intermittent Ethanol Exposure Dysregulates Nucleus Basalis Magnocellularis Afferents in the Basolateral Amygdala.

Sarah E Sizer, Michaela E Price, Brian C Parrish, Samuel H Barth, Chelcie F Heaney, Kimberly F Raab-Graham, Brian A McCool

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sarah E SizerDepartment of Physiology and Pharmacology, Piedmont Triad Community Research Center (PTCRC), Wake Forest University School of Medicine, Winston-Salem, NC 27101.
Michaela E PriceDepartment of Physiology and Pharmacology, Piedmont Triad Community Research Center (PTCRC), Wake Forest University School of Medicine, Winston-Salem, NC 27101.
Brian C ParrishDepartment of Physiology and Pharmacology, Piedmont Triad Community Research Center (PTCRC), Wake Forest University School of Medicine, Winston-Salem, NC 27101.
Samuel H BarthDepartment of Physiology and Pharmacology, Piedmont Triad Community Research Center (PTCRC), Wake Forest University School of Medicine, Winston-Salem, NC 27101.
Chelcie F HeaneyDepartment of Physiology and Pharmacology, Piedmont Triad Community Research Center (PTCRC), Wake Forest University School of Medicine, Winston-Salem, NC 27101.
Kimberly F Raab-GrahamDepartment of Physiology and Pharmacology, Piedmont Triad Community Research Center (PTCRC), Wake Forest University School of Medicine, Winston-Salem, NC 27101.ORCID https://orcid.org/0000-0001-6502-057X
Brian A McCoolDepartment of Physiology and Pharmacology, Piedmont Triad Community Research Center (PTCRC), Wake Forest University School of Medicine, Winston-Salem, NC 27101 bmccool@wakehealth.edu.ORCID https://orcid.org/0000-0002-1002-9435
Wake Forest University · US

Funding

Wake Forest Translational Alcohol Research Center (WF-TARC)P50AA026117 · NIAAA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Colleen A Hanlon · 2018 to 2026
$16.2M
MULTI-DISCIPLINARY TRAINING IN THE BIOLOGY OF ALCOHOLISMT32AA007565 · NIAAA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI BRIAN A MCCOOL · 1994 to 2026
$10.1M
The Ethanol - Anxiety Interaction: Cellular MechanismsR01AA014445 · NIAAA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI MCCOOL, BRIAN A · 2004 to 2023
$5.2M
Dissecting the Role of Nucleus Basalis Magnocellularis Circuitry in Basolateral Amygdala Physiology and Regulation of Anxiety Following Chronic Ethanol Exposure and WithdrawalF31AA028722 · NIAAA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI SIZER, SARAH ELIZABETH · 2021 to 2022
$72k
NIAAA NIH HHS F31 AA028722NIAAA NIH HHS P50 AA026117NIAAA NIH HHS R01 AA014445NIAAA NIH HHS T32 AA007565
6 · The paper itself

Abstract

Nucleus basalis magnocellularis (NBM) cholinergic projections to the basolateral amygdala (BLA) regulate the acquisition and consolidation of fear-like and anxiety-like behaviors. However, it is unclear whether the alterations in the NBM-BLA circuit promote negative affect during ethanol withdrawal (WD). Therefore, we performed

Indexed as

Basolateral Nuclear ComplexSubstance Withdrawal SyndromeAmygdalaAnimalsBasal Nucleus of MeynertEthanolMaleRatsRats, Sprague-DawleyEthanolacetylcholineamygdalabasal forebrainethanolGABAglutamate

Identifiers

PMID36280288
PMCPMC9668348
OpenAlexW4307234791

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.