Evidence map›Paper›PMID 36280248›Full record

ArticleCMAJ open

Maternal and neonatal outcomes in pregnancies with type 2 diabetes in First Nation and other Manitoban people: a population-based study.

Jennifer M Yamamoto, Christy Pylypjuk, Elizabeth Sellers, Lorraine McLeod, Brandy Wicklow, Monica Sirski, Heather Prior, Chelsea Ruth

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in CMAJ open. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jennifer M YamamotoDepartment of Internal Medicine (Yamamoto), University of Manitoba; Children's Hospital Research Institute of Manitoba (Yamamoto, Pylypjuk, Sellers, Wicklow); Departments of Obstetrics, Gynecology and Reproductive Sciences (Pylypjuk), and Pediatrics and Child Health (Sellers, Wicklow, Ruth), University of Manitoba; First Nations Health and Social Secretariat of Manitoba (McLeod); Manitoba Centre for Health Policy (Sirski, Prior, Ruth), University of Manitoba, Winnipeg, Man.
Christy PylypjukDepartment of Internal Medicine (Yamamoto), University of Manitoba; Children's Hospital Research Institute of Manitoba (Yamamoto, Pylypjuk, Sellers, Wicklow); Departments of Obstetrics, Gynecology and Reproductive Sciences (Pylypjuk), and Pediatrics and Child Health (Sellers, Wicklow, Ruth), University of Manitoba; First Nations Health and Social Secretariat of Manitoba (McLeod); Manitoba Centre for Health Policy (Sirski, Prior, Ruth), University of Manitoba, Winnipeg, Man.
Elizabeth SellersDepartment of Internal Medicine (Yamamoto), University of Manitoba; Children's Hospital Research Institute of Manitoba (Yamamoto, Pylypjuk, Sellers, Wicklow); Departments of Obstetrics, Gynecology and Reproductive Sciences (Pylypjuk), and Pediatrics and Child Health (Sellers, Wicklow, Ruth), University of Manitoba; First Nations Health and Social Secretariat of Manitoba (McLeod); Manitoba Centre for Health Policy (Sirski, Prior, Ruth), University of Manitoba, Winnipeg, Man.
Lorraine McLeodDepartment of Internal Medicine (Yamamoto), University of Manitoba; Children's Hospital Research Institute of Manitoba (Yamamoto, Pylypjuk, Sellers, Wicklow); Departments of Obstetrics, Gynecology and Reproductive Sciences (Pylypjuk), and Pediatrics and Child Health (Sellers, Wicklow, Ruth), University of Manitoba; First Nations Health and Social Secretariat of Manitoba (McLeod); Manitoba Centre for Health Policy (Sirski, Prior, Ruth), University of Manitoba, Winnipeg, Man.
Brandy WicklowDepartment of Internal Medicine (Yamamoto), University of Manitoba; Children's Hospital Research Institute of Manitoba (Yamamoto, Pylypjuk, Sellers, Wicklow); Departments of Obstetrics, Gynecology and Reproductive Sciences (Pylypjuk), and Pediatrics and Child Health (Sellers, Wicklow, Ruth), University of Manitoba; First Nations Health and Social Secretariat of Manitoba (McLeod); Manitoba Centre for Health Policy (Sirski, Prior, Ruth), University of Manitoba, Winnipeg, Man.
Monica SirskiDepartment of Internal Medicine (Yamamoto), University of Manitoba; Children's Hospital Research Institute of Manitoba (Yamamoto, Pylypjuk, Sellers, Wicklow); Departments of Obstetrics, Gynecology and Reproductive Sciences (Pylypjuk), and Pediatrics and Child Health (Sellers, Wicklow, Ruth), University of Manitoba; First Nations Health and Social Secretariat of Manitoba (McLeod); Manitoba Centre for Health Policy (Sirski, Prior, Ruth), University of Manitoba, Winnipeg, Man.
Heather PriorDepartment of Internal Medicine (Yamamoto), University of Manitoba; Children's Hospital Research Institute of Manitoba (Yamamoto, Pylypjuk, Sellers, Wicklow); Departments of Obstetrics, Gynecology and Reproductive Sciences (Pylypjuk), and Pediatrics and Child Health (Sellers, Wicklow, Ruth), University of Manitoba; First Nations Health and Social Secretariat of Manitoba (McLeod); Manitoba Centre for Health Policy (Sirski, Prior, Ruth), University of Manitoba, Winnipeg, Man.
Chelsea RuthDepartment of Internal Medicine (Yamamoto), University of Manitoba; Children's Hospital Research Institute of Manitoba (Yamamoto, Pylypjuk, Sellers, Wicklow); Departments of Obstetrics, Gynecology and Reproductive Sciences (Pylypjuk), and Pediatrics and Child Health (Sellers, Wicklow, Ruth), University of Manitoba; First Nations Health and Social Secretariat of Manitoba (McLeod); Manitoba Centre for Health Policy (Sirski, Prior, Ruth), University of Manitoba, Winnipeg, Man. Chelsea.ruth@umanitoba.ca.
Children's Hospital Research Institute of Manitoba · CAUniversity of Manitoba · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFirst Nation people living in Canada experience a high prevalence of type 2 diabetes in pregnancy. In this study, we aimed to describe maternal and neonatal outcomes in First Nation and all other females with type 2 diabetes living in Manitoba, Canada.

methodsThis was a population-level retrospective cohort study using linked administrative data from Manitoba (2012-2017). We compared First Nation females with type 2 diabetes with all other Manitoban females with type 2 diabetes, using relative risks (RRs) and 95% confidence intervals (CIs).

resultsA total of 2181 females with type 2 diabetes were included, and 1218 (55.8%) were First Nation. First Nation females with type 2 diabetes were significantly more likely to experience stillbirth (RR 2.14, 95% CI 1.11-4.13) and perinatal death (RR 2.39, 95% CI 1.37-4.17) than all other Manitoban females with type 2 diabetes. Offspring of First Nation females with type 2 diabetes had a higher risk of most neonatal complications than offspring of all other Manitoban females with type 2 diabetes, including a higher risk of congenital malformations (RR 1.97, 95% CI 1.30-2.99), but First Nation people did not have a higher risk of most maternal complications.

interpretationFirst Nation pregnant individuals living with type 2 diabetes experienced a higher risk for adverse pregnancy outcomes than all other Manitoban females with type 2 diabetes. Additional studies are needed to identify both high-risk and protective factors for pregnancy complications in First Nation people living with type 2 diabetes in pregnancy.

Indexed as

Diabetes Mellitus, Type 2Pregnancy ComplicationsFemaleHumansInfant, NewbornPregnancyPregnancy OutcomeRetrospective StudiesStillbirth

Identifiers

PMID36280248
PMCPMC9640167
OpenAlexW4307342072

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.