SynthesisNeurotoxicology2022
Air pollution, depressive and anxiety disorders, and brain effects: A systematic review.
Synthesis in Neurotoxicology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 93 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
93 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review of air pollution exposure and brain structure and function during development.Environmental research · 2025Pooled it
- Atmospheric Aerosol Neurotoxicity and Parkinson's Disease: Mechanisms and Perspectives.Journal of biochemical and molecular toxicology · 2026Review
- Association between household environment and the risk of depression and anxiety among women in Bangladesh: analysis of the Bangladesh Demographic and Health Survey (2022).The Lancet regional health. Southeast Asia · 2026Article
- PMiScience · 2026Review
- The Relationship between Air Pollution Exposure, Genetic Liability for Schizophrenia, and Brain Outcomes in the ABCD Study.Schizophrenia bulletin · 2026Article
- Within- and between-study site variations in ambient air pollution exposure at ages 9-10 years in the Adolescent Brain Cognitive Development (ABCD) Study.Environmental epidemiology (Philadelphia, Pa.) · 2026Article
- Wearable Personal PMmedRxiv : the preprint server for health sciences · 2026Article
- Radon-related increases in depressive symptoms are explained by amygdala morphology and external locus of control.Neurotoxicology · 2026Article
- Revisiting 'environmental effects': Directions for multidisciplinary investigations of air quality and psychopathology.Clinical psychological science : a journal of the Association for Psychological Science · 2026Article
- Housing Displacement, Employment Disruption, and Mental Health After the 2023 Maui Wildfires.JAMA psychiatry · 2026Article
- The physiological effects of APOE genotype in healthy young/middle-aged individuals.Biological reviews of the Cambridge Philosophical Society · 2026Article
- Associations between residential segregation, ambient air pollution, and hippocampal features in recent trauma survivors.Translational psychiatry · 2026Article
- Article
- Association of short-term ambient environmental exposures with suicide and drug overdose deaths among U.S. veterans.American journal of epidemiology · 2026Article
- Association of air pollution and depressive symptoms with cardiometabolic Multimorbidity in middle-aged and older adults: an analysis based on the China health and retirement longitudinal study (CHARLS).Acta diabetologica · 2026Article
- Impacts of air pollution on farmers' subjective satisfaction in China's ore and agricultural zone.Scientific reports · 2026Article
- Differential association between ambient PMiScience · 2026Article
- Impact of air pollution on mental health in bangladesh: a comparison between Dhaka and Rajshahi.Scientific reports · 2026Article
- Environmental pollutants and the gut microbiota: mechanistic links from exposure to systemic disease.Frontiers in microbiology · 2026Review
- Particulate matter increases bone morphogenetic protein 2 in lung fibroblasts.American journal of physiology. Lung cellular and molecular physiology · 2026Article
33 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Accumulating data suggest that air pollution increases the risk of internalizing psychopathology, including anxiety and depressive disorders. Moreover, the link between air pollution and poor mental health may relate to neurostructural and neurofunctional changes. We systematically reviewed the MEDLINE database in September 2021 for original articles reporting effects of air pollution on 1) internalizing symptoms and behaviors (anxiety or depression) and 2) frontolimbic brain regions (i.e., hippocampus, amygdala, prefrontal cortex). One hundred and eleven articles on mental health (76% human, 24% animals) and 92 on brain structure and function (11% human, 86% animals) were identified. For literature search 1, the most common pollutants examined were PM
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.