Evidence map›Paper›PMID 36280096›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2022

Hansen's disease (leprosy) in Japan, 1947-2020: an epidemiologic study during the declining phase to elimination.

Rie R Yotsu, Yuji Miyamoto, Shuichi Mori, Manabu Ato, Mariko Sugawara-Mikami, Sayaka Yamaguchi, Masashi Yamazaki, Motoaki Ozaki, Norihisa Ishii

Abstract read
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In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rie R YotsuDepartment of Tropical Medicine, Tulane School of Public Health and Tropical Medicine, New Orleans, USA; Department of Dermatology, National Center for Global Health and Medicine, Tokyo, Japan; School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan. Electronic address: ryotsu@tulane.edu.
Yuji MiyamotoLeprosy Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Shuichi MoriLeprosy Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Manabu AtoLeprosy Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Mariko Sugawara-MikamiWest Yokohama Sugawara Dermatology Clinic, Yokohama, Japan; Department of Clinical Laboratory Science, Faculty of Medicine Technology, Teikyo University, Tokyo, Japan.
Sayaka YamaguchiDepartment of Dermatology, University of the Ryukyus, Okinawa, Japan.
Masashi YamazakiNational Sanatorium Tamazenshoen, Tokyo, Japan.
Motoaki OzakiNational Sanatorium Nagashima-Aiseien, Setouchi-shi, Japan.
Norihisa IshiiLeprosy Research Center, National Institute of Infectious Diseases, Tokyo, Japan; National Sanatorium Tamazenshoen, Tokyo, Japan.

Funding

MIND-the-SKIN Project: Multi-functional Innovative Digital Toolkit for the Skin Diseases in LMICs and BeyondR21TW011860 · FIC · TULANE UNIVERSITY OF LOUISIANA · PI YOTSU, RIE · 2021 to 2022
$356k
FIC NIH HHS R21 TW011860
6 · The paper itself

Abstract

objectivesLeprosy, or Hansen's disease was a major public health problem in Japan in the early 20th century. Today, the number of new cases has decreased significantly. We aimed to investigate the trends of leprosy in Japan over the past 73 years and the challenges faced in recent years.

methodsWe assessed the data on newly registered cases of leprosy from 1947 to 2020.

resultsA total of 10,796 newly registered cases of leprosy were reported during the study period, of which 7573 were registered in mainland Japan, 2962 in Okinawa, and 250 were of foreign origin. Most autochthonous cases were born before 1950 in mainland Japan and before 1975 in Okinawa. The number of nonautochthonous cases surpassed that of autochthonous cases in 1992. Nonautochthonous cases originated from 26 countries, particularly Brazil and the Philippines. Three cases of antimicrobial resistance have been detected among nonautochthonous cases since 2004.

conclusionOur data suggest that ongoing transmission of leprosy likely ceased in the 1940s in mainland Japan and in the 1970s in Okinawa. With the recent rise of nonautochthonous cases with globalization, continuous surveillance and efforts to maintain leprosy services within the country are necessary even after reaching the state of elimination.

Indexed as

LeprosyBrazilEpidemiologic StudiesHumansJapanPublic HealthBirth yearEpidemiologyHansen's diseaseJapanLeprosy

Identifiers

PMID36280096
PMCPMC9798910

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.