Evidence map›Paper›PMID 36279220›Full record

Trial reportJournal of consulting and clinical psychology2022

Change during cognitive and exposure phases of cognitive-behavioral therapy for autistic youth with anxiety disorders.

Andrew G Guzick, Sophie C Schneider, Philip C Kendall, Jeffrey J Wood, Connor M Kerns, Brent J Small, Ye Eun Park, Sandra L Cepeda, Eric A Storch

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of consulting and clinical psychology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Cognitive Behavioral Therapy for Children and Adolescents with Anxiety Disorders.Child and adolescent psychiatric clinics of North America · 2023
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Andrew G GuzickDepartment of Psychiatry and Behavioral Sciences, Baylor College of Medicine.ORCID 0000-0002-4159-9203
Sophie C SchneiderDepartment of Psychiatry and Behavioral Sciences, Baylor College of Medicine.ORCID 0000-0002-1469-7764
Philip C KendallDepartment of Psychology and Neuroscience, Temple University.ORCID 0000-0001-7034-6961
Jeffrey J WoodDepartment of Education, University of California, Los Angeles.ORCID 0000-0002-0759-6156
Connor M KernsDepartment of Psychology, University of British Columbia.ORCID 0000-0003-0832-8329
Brent J SmallSchool of Aging Studies, College of Behavioral and Community Sciences, University of South Florida.ORCID 0000-0002-7444-4689
Ye Eun ParkDepartment of Psychiatry and Behavioral Sciences, Baylor College of Medicine.
Sandra L CepedaDepartment of Psychiatry and Behavioral Sciences, Baylor College of Medicine.
Eric A StorchDepartment of Psychiatry and Behavioral Sciences, Baylor College of Medicine.
Baylor College of Medicine · USTemple University · USUniversity of British Columbia · CAUniversity of California, Los Angeles · USUniversity of South Florida · US

Funding

Preclinical and Clincial OutcomesP50HD103555 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI MIRJANA MALETIC-SAVATIC · 2020 to 2026
$9.9M
1/3 Treatment of Anxiety in Autism Spectrum DisorderR01HD080098 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WOOD, JEFFREY JAMES · 2014 to 2016
$663k
3/3 Treatment of anxiety in autism spectrum disorderR01HD080097 · NICHD · TEMPLE UNIV OF THE COMMONWEALTH · PI KENDALL, PHILIP C · 2014 to 2016
$563k
2/3 Treatment of Anxiety in Autism Spectrum DisorderR01HD080096 · NICHD · UNIVERSITY OF SOUTH FLORIDA · PI STORCH, ERIC A. · 2014 to 2016
$471k
NICHD NIH HHS P50 HD103555NICHD NIH HHS R01 HD080096NICHD NIH HHS R01 HD080097NICHD NIH HHS R01 HD080098
6 · The paper itself

Abstract

objectiveTo evaluate improvement during the (a) cognitive and (b) exposure therapy phases of cognitive-behavioral therapy (CBT) for autistic youth with anxiety disorders.

methodParticipants were 148 autistic youth (aged 7-13; 77% male; 64% White) with clinically significant anxiety who were randomized to standard or adapted CBT. Clinician-rated anxiety severity was recorded at each appointment. Trajectories of change during (a) the cognitive phase and (b) the exposure phase of treatment were analyzed using piecewise multilevel modeling.

resultsCompared to the psychoeducation and cognitive therapy phases, the exposure phase corresponded with significantly more rapid symptom reduction, b = -.11, 95% CI [-.13, -.071]. This finding was true for standard CBT, which included nine sessions prior to exposure initiation (on average), as well as for CBT personalized for autistic youth, which introduced exposure following the fifth session (on average). In contrast, compared with improvements during initial psychoeducation sessions, the introduction of cognitive skills corresponded with significantly slower symptom reduction, b = .066, 95% CI [.020, .11]. This finding was also true for both adapted and standard CBT.

conclusionsResults underscore the central role of exposure in the treatment of anxiety among autistic youth and question the utility of cognitive strategies without subsequent practice of these skills during exposure. Assuming a working relationship, therapists should consider moving through the preexposure coping phase of CBT quickly. Future research should evaluate the extent to which exposure can maintain its potency while minimizing coping skill preparation. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

Indexed as

Autistic DisorderCognitive Behavioral TherapyAdaptation, PsychologicalAdolescentAnxiety DisordersCognitionFemaleHumansMale

Identifiers

PMID36279220
PMCPMC9891710
OpenAlexW4307286747

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.