Evidence map›Paper›PMID 36279007›Full record

ReviewInnere Medizin (Heidelberg, Germany)2022

[Evidence of positive care effects by digital health apps-methodological challenges and approaches].

Inke R König, Mirja Mittermaier, Christian Sina, Matthias Raspe, Patrick Stais, Thomas Gamstätter, Philipp Stachwitz, Sebastian Wolfrum, Jutta G Richter, Martin Möckel and 1 more

Abstract readEnglish AbstractReview
PubMed Publisher
In one paragraph

Review in Innere Medizin (Heidelberg, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Review
  3. [Relevance of eHealth Literacy (eHL) for Health Services Research and Practice - Part I].Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)) · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. [Community-based Disease Prevention and Health Promotion: Promoting Digital Health Literacy among People in Precarious Living Conditions].Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)) · 2025
    Article
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Inke R KönigInstitut für Medizinische Biometrie und Statistik, Universität zu Lübeck, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Lübeck, Deutschland.
Mirja MittermaierMedizinische Klinik m.S. Infektiologie und Pneumologie, Charité - Universitätsmedizin Berlin, Berlin, Deutschland.
Christian SinaInstitut für Ernährungsmedizin, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Lübeck, Deutschland.
Matthias RaspeMedizinische Klinik m.S. Infektiologie und Pneumologie, Charité - Universitätsmedizin Berlin, Berlin, Deutschland.
Patrick StaisMedizinische Klinik 3, Lungen- und Bronchialheilkunde, Lungen-Thorax-Zentrum Nordrhein, Moers, Deutschland.
Thomas GamstätterDeutsche Gesellschaft für Innere Medizin e. V., Wiesbaden, Deutschland.
Philipp StachwitzDeutsche Gesellschaft für Innere Medizin e. V., Wiesbaden, Deutschland.
Sebastian WolfrumInterdisziplinäre Notaufnahme, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Lübeck, Deutschland.
Jutta G RichterPoliklinik und Funktionsbereich Rheumatologie & Hiller-Forschungszentrum Rheumatologie, Medizinische Fakultät, Heinrich-Heine-Universität Düsseldorf, Universitätsklinikum Düsseldorf, Düsseldorf, Deutschland.
Martin MöckelNotfall- und Akutmedizin, Zentrale Notaufnahmen und Chest Pain Units, Campus Mitte und Virchow-Klinikum, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Deutschland. martin.moeckel@charite.de.
Arbeitsgruppe Digitale Gesundheitsanwendungen (DiGA) und künstliche Intelligenz (KI) in Leitlinien der Kommission Digitale Transformation der Deutschen Gesellschaft für Innere Medizin (DGIM)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since 2020, digital health applications (DiGA) can be prescribed at the expense of the German statutory health insurance (SHI) system after undergoing an approval procedure by the Federal Institute for Drugs and Medical Devices (BfArM). DiGA can be approved provisionally for 1 year (with the option of extension) or permanently. The latter is dependent on scientific evidence of a positive effect on care, which can be a medical benefit or a patient-relevant structural and procedural improvement in care. However, it is apparent that the investigation of DiGA in scientific studies is challenging, as they are often complex interventions whose success also includes user and prescriber factors. In addition, health services research data underpinning the benefits of DiGA are lacking to date. In the current article, methodological considerations for DiGA research are presented, and a selection of internal medicine DiGAs is used to critically discuss current research practice.

Indexed as

Health Services ResearchNational Health ProgramsDigital TechnologyHumansDigital health applications/internal medicineHealth services researchMedical benefitPatient-relevant structural and procedural improvementStudy design

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.