Evidence map›Paper›PMID 36278868›Full record

ReviewACR open rheumatology2022

Optimizing Medication Use in Older Adults With Rheumatic Musculoskeletal Diseases: Deprescribing as an Approach When Less May Be More.

Jiha Lee, Namrata Singh, Shelly L Gray, Una E Makris

Open access · goldAbstract readReview
In one paragraph

Review in ACR open rheumatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  5. Review
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  8. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Jiha LeeJUniversity of Michigan, Ann Arbor.ORCID https://orcid.org/0000-0002-6402-6563
Namrata SinghUniversity of Washington, Seattle.
Shelly L GrayUniversity of Washington, Seattle.
Una E MakrisUniversity of Texas Southwestern Medical Center and VA North Texas Health Care System, Dallas.
University of Washington · USSouthwestern Medical Center · USUniversity of Michigan · US

Funding

Translational pharmacoepidemiology: neuroprotection and neurotoxicity of antihypertensives and strong anticholinergicsU19AG066567 · NIA · KAISER FOUNDATION RESEARCH INSTITUTE · PI Christine L MacDonald · 2021 to 2026
$80.4M
Research Education CoreP30AG024824 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Neil Alexander · 2004 to 2026
$29.2M
U.S. Deprescribing Research NetworkR24AG064025 · NIA · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI BOYD, CYNTHIA MELINDA, STEINMAN, MICHAEL A. · 2019 to 2023
$9.9M
Improving shared decision-making around the use of disease modifying anti-rheumatic drugs in patients with rheumatoid arthritis and cancerK23AR079588 · NIAMS · UNIVERSITY OF WASHINGTON · PI Namrata Singh · 2022 to 2026
$821k
Evaluation of treatment patterns and prescription medication use among older adults with late-onset rheumatoid arthritisR03AG067975 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LEE, JIHA · 2020 to 2021
$308k
MOTIVATE to Improve Outcomes for Older Veterans with Musculoskeletal Pain and DepressionI01HX003350 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI UNA E. MAKRIS · 2022 to 2026
–
Improving Outcomes for Older Veterans with Chronic Back Pain and DepressionIK2HX001916 · VA · VA NORTH TEXAS HEALTH CARE SYSTEM · PI MAKRIS, UNA E. · 2020 to 2021
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ACL HHS U01CE002967CDC HHS U01CE002967HSRD VA I01 HX003350HSRD VA IK2 HX001916NIAMS NIH HHS K23 AR079588NIA NIH HHS K23AR079588NIA NIH HHS P30 AG024824NIA NIH HHS P30AG024824NIA NIH HHS R03 AG067975NIA NIH HHS R03AG067975NIA NIH HHS R24 AG064025NIA NIH HHS R24AG064025NIA NIH HHS U19 AG066567NIA NIH HHS U19AG066567
6 · The paper itself

Abstract

The world population is aging, and the rheumatology workforce must be prepared to care for medically complex older adults. We can learn from our colleagues and experts in geriatrics about how to best manage multimorbidity, polypharmacy, geriatric syndromes, and shifting priorities of older adults in the context of delivering care for rheumatic and musculoskeletal diseases (RMDs). Polypharmacy, a common occurrence in an aging population with multimorbidity, affects half of older adults with RMDs and is associated with increased risk of morbidity and mortality. In addition, potentially inappropriate medications that should be avoided under most circumstances is common in the RMD population. In recent years, deprescribing, known as the process of tapering, stopping, discontinuing, or withdrawing drugs, has been introduced as an approach to improve appropriate medication use among older adults and the outcomes that are important to them. As the rheumatology patient population ages globally, it is imperative to understand the burden of polypharmacy and the potential of deprescribing to improve medication use in older adults with RMDs. We encourage the rheumatology community to implement geriatric principles, when possible, as we move toward becoming an age-friendly health care specialty.

Identifiers

PMID36278868
PMCPMC9746667
OpenAlexW4307178186

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.