Evidence map›Paper›PMID 36278712›Full record

ArticleBiomimetics (Basel, Switzerland)2022

Simple Microcontact Printing Technique to Obtain Cell Patterns by Lithography Using Grayscale, Photopolymer Flexographic Mold, and PDMS.

Rocio Gimenez, Camilo Pérez-Sosa, Natalia Bourguignon, Santiago Miriuka, Shekhar Bhansali, Carlos R Arroyo, Alexis Debut, Betiana Lerner, Maximiliano S Pérez

Abstract read
In one paragraph

Article in Biomimetics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rocio GimenezIREN Center, National Technological University, Buenos Aires 1706, Argentina.
Camilo Pérez-SosaIREN Center, National Technological University, Buenos Aires 1706, Argentina.
Natalia BourguignonIREN Center, National Technological University, Buenos Aires 1706, Argentina.
Santiago MiriukaLIAN-CONICET-FLENI, Ruta 9 Km 52, 5, Belén de Escobar 1625, Argentina.
Shekhar BhansaliDepartment of Electrical and Computer Engineering, Florida International University, Miami, FL 33174, USA.
Carlos R ArroyoCentro de Nanociencia y Nanotecnología, Universidad de las Fuerzas Armadas ESPE, Sangolqui P.O. Box 171-5-231B, Ecuador.
Alexis DebutCentro de Nanociencia y Nanotecnología, Universidad de las Fuerzas Armadas ESPE, Sangolqui P.O. Box 171-5-231B, Ecuador.ORCID 0000-0002-8269-7619
Betiana LernerIREN Center, National Technological University, Buenos Aires 1706, Argentina.ORCID 0000-0003-3341-5686
Maximiliano S PérezIREN Center, National Technological University, Buenos Aires 1706, Argentina.

Funding

National Scientific and Technical Research Council PIP 2021-2023 11220200101707CONIMHD NIH HHS 800013656
6 · The paper itself

Abstract

Microcontact printing using PDMS embossing tools and its variations have aroused the interest of a wide spectrum of research fields, hence the feasibility of defining micro and nanoscale patterns. In this work, we have proposed and demonstrated a novel lithography method based on grayscale patterns printed in a flexographic photopolymer mold and transferred to epoxy resin and a single PDMS stamp to obtain different microprint pattern structures. The geometry of the patterns can be modified by adjusting the layout and grayscale of the stamp patterns. The functionality of this contact printing methodology was validated by generating human induced pluripotent stem cells (hiPSC) patterns. These specific micropatterns can be very useful for achieving complex differentiation in cell lines such as hiPSC. Microfabrication through the new technique provides a promising alternative to conventional lithography for constructing complex aligned surfaces; these structures could be used as components of biological patterns or microfluidic devices.

Indexed as

3D patternscontact printingflexographic photopolymer moldgrayscalePDMS stamp

Identifiers

PMID36278712
PMCPMC9624307

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.