Evidence map›Paper›PMID 36278693›Full record

ReviewNeurology international2022

Diffusion Tensor Imaging as a Prognostic Tool for Recovery in Acute and Hyperacute Stroke.

Foteini Christidi, Dimitrios Tsiptsios, Aggeliki Fotiadou, Sofia Kitmeridou, Stella Karatzetzou, Konstantinos Tsamakis, Anastasia Sousanidou, Evlampia A Psatha, Efstratios Karavasilis, Ioannis Seimenis and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in Neurology international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Foteini ChristidiNeurology Department, School of Medicine, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Dimitrios TsiptsiosNeurology Department, School of Medicine, Democritus University of Thrace, 68100 Alexandroupolis, Greece.ORCID 0000-0002-1601-8788
Aggeliki FotiadouNeurology Department, School of Medicine, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Sofia KitmeridouNeurology Department, School of Medicine, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Stella KaratzetzouNeurology Department, School of Medicine, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Konstantinos TsamakisInstitute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London SE5 8AB, UK.
Anastasia SousanidouNeurology Department, School of Medicine, Democritus University of Thrace, 68100 Alexandroupolis, Greece.ORCID 0000-0003-2092-6313
Evlampia A PsathaDepartment of Radiology, School of Medicine, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Efstratios KaravasilisSchool of Medicine, Democritus University of Thrace, 68100 Alexandroupolis, Greece.ORCID 0000-0002-7291-2231
Ioannis SeimenisMedical Physics Laboratory, School of Medicine, National and Kapodistrian University, 11527 Athens, Greece.ORCID 0000-0003-3665-5271
Christos KokkotisDepartment of Physical Education and Sport Science, Democritus University of Thrace, 69100 Komotini, Greece.
Nikolaos AggelousisDepartment of Physical Education and Sport Science, Democritus University of Thrace, 69100 Komotini, Greece.ORCID 0000-0001-5108-7335
Konstantinos VadikoliasNeurology Department, School of Medicine, Democritus University of Thrace, 68100 Alexandroupolis, Greece.ORCID 0000-0003-0484-369X
Democritus University of Thrace · GRKing's College London · GBNational and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stroke represents a major cause of mortality and long-term disability among adult populations, leaving a devastating socioeconomic impact globally. Clinical manifestation of stroke is characterized by great diversity, ranging from minor disability to considerable neurological impairment interfering with activities of daily living and even death. Prognostic ambiguity has stimulated the interest for implementing stroke recovery biomarkers, including those provided by structural neuroimaging techniques, i.e., diffusion tensor imaging (DTI) and tractography for the study of white matter (WM) integrity. Considering the necessity of prompt and accurate prognosis in stroke survivors along with the potential capacity of DTI as a relevant imaging biomarker, the purpose of our study was to review the pertinent literature published within the last decade regarding DTI as a prognostic tool for recovery in acute and hyperacute stroke. We conducted a thorough literature search in two databases (MEDLINE and Science Direct) in order to trace all relevant studies published between 1 January 2012 and 16 March 2022 using predefined terms as key words. Only full-text human studies published in the English language were included. Forty-four studies were identified and are included in this review. We present main findings and by describing several methodological issues, we highlight shortcomings and gaps in the current literature so that research priorities for future research can be outlined. Our review suggests that DTI can track longitudinal changes and identify prognostic correlates in acute and hyperacute stroke patients.

Indexed as

acute strokebiomarkersdiffusion tensor imaginghyperacute strokestroke prognosistractography

Identifiers

PMID36278693
PMCPMC9589952
OpenAlexW4307270129

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.