ReviewJournal of functional biomaterials2022
Zinc-Based Biodegradable Materials for Orthopaedic Internal Fixation.
Review in Journal of functional biomaterials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 66 citations in OpenAlex.
- Biophysical signal-driven scaffold design for stem cell-guided osteochondral regeneration.Bioactive materials · 2026Review
- Sculpting the Future of Bone: The Evolution of Absorbable Materials in Orthopedics.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- [Application progress of customized steel plates in osteotomy and orthopedic treatment of knee osteoarthritis].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025Review
- An In Silico Model to Examine the Interaction Between Implant Degradation and Fracture Healing Under Mechanical Loading.Annals of biomedical engineering · 2025Article
- Enhanced Long-Term Antibacterial and Osteogenic Properties of Silver-Loaded Titanium Dioxide Nanotube Arrays for Implant Applications.International journal of nanomedicine · 2025Article
- Hybrid additive manufacturing for Zn-Mg casting for biomedical application.In vitro models · 2024Article
- Enhanced Experimental Setup and Methodology for the Investigation of Corrosion Fatigue in Metallic Biodegradable Implant Materials.Materials (Basel, Switzerland) · 2024Article
- Review
- Functional Biomaterials and Digital Technologies in Dentistry: From Bench to Bedside.Journal of functional biomaterials · 2024Article
- Characterization of hFOB 1.19 Cell Line for Studying Zn-Based Degradable Metallic Biomaterials.Materials (Basel, Switzerland) · 2024Article
- Article
- Biodegradable Implants for Internal Fixation of Fractures and Accelerated Bone Regeneration.ACS omega · 2023Review
- Biomechanical Study and Analysis for Cardiovascular/Skeletal Materials and Devices.Journal of functional biomaterials · 2023Article
- A Comprehensive Review of the Current Research Status of Biodegradable Zinc Alloys and Composites for Biomedical Applications.Materials (Basel, Switzerland) · 2023Review
- Review
- Biodegradable Materials for Tissue Engineering: Development, Classification and Current Applications.Journal of functional biomaterials · 2023Review
- 3D Printing Technologies in Personalized Medicine, Nanomedicines, and Biopharmaceuticals.Pharmaceutics · 2023Review
- Recent Developments in Zn-Based Biodegradable Materials for Biomedical Applications.Journal of functional biomaterials · 2022Review
- Structure, Biodegradation, and In Vitro Bioactivity of Zn-1%Mg Alloy Strengthened by High-Pressure Torsion.Materials (Basel, Switzerland) · 2022Article
- Biomaterials-based engineering of the bone microenvironment for osteoporosis therapy.Journal of tissue engineeringReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Traditional inert materials used in internal fixation have caused many complications and generally require removal with secondary surgeries. Biodegradable materials, such as magnesium (Mg)-, iron (Fe)- and zinc (Zn)-based alloys, open up a new pathway to address those issues. During the last decades, Mg-based alloys have attracted much attention by researchers. However, the issues with an over-fast degradation rate and release of hydrogen still need to be overcome. Zn alloys have comparable mechanical properties with traditional metal materials, e.g., titanium (Ti), and have a moderate degradation rate, potentially serving as a good candidate for internal fixation materials, especially at load-bearing sites of the skeleton. Emerging Zn-based alloys and composites have been developed in recent years and in vitro and in vivo studies have been performed to explore their biodegradability, mechanical property, and biocompatibility in order to move towards the ultimate goal of clinical application in fracture fixation. This article seeks to offer a review of related research progress on Zn-based biodegradable materials, which may provide a useful reference for future studies on Zn-based biodegradable materials targeting applications in orthopedic internal fixation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.