Evidence map›Paper›PMID 36278591›Full record

ArticleDiseases (Basel, Switzerland)2022

Associations between Insomnia Symptoms and Anxiety Symptoms in Adults in a Community Sample of Southeastern Pennsylvania, USA.

Sadia B Ghani, Ashna Kapoor, Andrew S Tubbs, Chloe C A Wills, Jordan F Karp, Michael L Perlis, William D S Killgore, Fabian-Xosé Fernandez, Michael A Grandner

Abstract read
In one paragraph

Article in Diseases (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Cognitive and behavioral therapies for insomnia: must they always be in bed together?Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  4. Clustering and drivers of symptoms observed at week six after antidepressant treatment in depressed outpatients.European psychiatry : the journal of the Association of European Psychiatrists · 2025
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sadia B GhaniSleep and Health Research Program, Department of Psychiatry, University of Arizona College of Medicine, Tucson, AZ 85724, USA.ORCID 0000-0001-9236-5629
Ashna KapoorSleep and Health Research Program, Department of Psychiatry, University of Arizona College of Medicine, Tucson, AZ 85724, USA.
Andrew S TubbsSleep and Health Research Program, Department of Psychiatry, University of Arizona College of Medicine, Tucson, AZ 85724, USA.ORCID 0000-0003-3799-5972
Chloe C A WillsSleep and Health Research Program, Department of Psychiatry, University of Arizona College of Medicine, Tucson, AZ 85724, USA.
Jordan F KarpDepartment of Psychiatry, University of Arizona College of Medicine, Tucson, AZ 85724, USA.
Michael L PerlisPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
William D S KillgoreSCAN Lab, Department of Psychiatry, University of Arizona College of Medicine, Tucson, AZ 85724, USA.ORCID 0000-0002-5328-0208
Fabian-Xosé FernandezDepartment of Psychology, University of Arizona, Tucson, AZ 85724, USA.ORCID 0000-0002-4288-5383
Michael A GrandnerSleep and Health Research Program, Department of Psychiatry, University of Arizona College of Medicine, Tucson, AZ 85724, USA.ORCID 0000-0002-4626-754X

Funding

PHYSIOLOGYT32HL007249 · NHLBI · UNIVERSITY OF ARIZONA · PI Brett A Colson, JOHN P KONHILAS · 1985 to 2026
$12.5M
Using Sleep Health to Optimize Smoking Cessation Treatment Response in HIV-Positive AdultsR01DA051321 · NIDA · UNIVERSITY OF ARIZONA · PI FANTRY, LORI E, GRANDNER, MICHAEL A · 2020 to 2024
$4.1M
Sleep and Cardiometabolic Health Disparities at the US/Mexico Border: The Nogales Cardiometabolic Health and Sleep (NoCHeS) StudyR01MD011600 · NIMHD · UNIVERSITY OF ARIZONA · PI GRANDNER, MICHAEL A · 2018 to 2022
$4.1M
Sleep and Health in the Social EnvironmentR21ES022931 · NIEHS · UNIVERSITY OF PENNSYLVANIA · PI GRANDNER, MICHAEL A · 2012 to 2013
$436k
NHLBI NIH HHS T32 HL007249NIDA NIH HHS R01 DA051321NIEHS NIH HHS R21 ES022931NIH HHS R01DA051321NIH HHS R01MD011600NIH HHS T32HL007249NIMHD NIH HHS R01 MD011600
6 · The paper itself

Abstract

Although insomnia is reliably associated with anxiety symptoms, aspects of insomnia may differentially relate to one anxiety symptom versus another. Therefore, treatment for insomnia comorbidity with anxiety might be individually tailored to optimize treatment response. Working from this hypothesis, we analyzed data from a survey of 1007 community-dwelling adults. Insomnia was measured using the Insomnia Severity Index (ISI), categorizing items as nighttime disturbances, daytime dysfunction, or self-perceived dissatisfaction. Anxiety symptoms were measured with the Generalized Anxiety Disorder 7-item questionnaire (GAD-7). Linear and binomial logistic regression were used and adjusted for covariates. Post hoc forward stepwise analyses determined which components of the insomnia contributed to individual anxiety symptoms. Significant associations between nighttime disturbance (β = 0.88 [0.44, 1.3]), daytime dysfunction (β = 1.30 [0.81, 1.80]), dissatisfaction (β = 1.20 [0.60, 1.7]) and total GAD-7 score were maintained after adjusting for covariates. Nighttime disturbance was associated with excess worrying, restlessness, irritability, and fear of catastrophe. Daytime dysfunction was associated with all symptoms except for fear of catastrophe, and self-perceived dissatisfaction was associated with all symptoms except irritability. Stepwise analyses revealed that daytime dysfunction and dissatisfaction were most consistently related to anxiety symptoms.Greater attention should be paid to daytime dysfunction in patients with insomnia and anxiety, as improving daytime functioning may improve anxiety.

Indexed as

anxietydaytime dysfunctioninsomniashort sleepsleep health

Identifiers

PMID36278591
PMCPMC9624306

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.