Evidence map›Paper›PMID 36278581›Full record

ArticleDiseases (Basel, Switzerland)2022

Evaluation of Xpert MTB/RIF Assay, MTB Culture and Line Probe Assay for the Detection of MDR Tuberculosis in AFB Smear Negative Specimens.

Chandri Lama, Sanjib Adhikari, Sanjeep Sapkota, Ramesh Sharma Regmi, Gokarna Raj Ghimire, Megha Raj Banjara, Prakash Ghimire, Komal Raj Rijal

Abstract read
In one paragraph

Article in Diseases (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chandri LamaCentral Department of Microbiology, Tribhuvan University, Kirtipur 44618, Nepal.
Sanjib AdhikariCentral Department of Microbiology, Tribhuvan University, Kirtipur 44618, Nepal.
Sanjeep SapkotaGuangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China.
Ramesh Sharma RegmiCentral Department of Microbiology, Tribhuvan University, Kirtipur 44618, Nepal.
Gokarna Raj GhimireNational TB Reference Laboratory, National Tuberculosis Centre, Thimi 44600, Nepal.
Megha Raj BanjaraCentral Department of Microbiology, Tribhuvan University, Kirtipur 44618, Nepal.
Prakash GhimireCentral Department of Microbiology, Tribhuvan University, Kirtipur 44618, Nepal.ORCID 0000-0003-2503-412X
Komal Raj RijalCentral Department of Microbiology, Tribhuvan University, Kirtipur 44618, Nepal.ORCID 0000-0001-6281-8236

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The global burden of tuberculosis (TB), particularly with multidrug resistance (MDR), is escalating and has become a major health challenge. It is well known that acid-fast bacilli (AFB) smear-negative TB patients are the major source of spreading TB to healthy individuals when left untreated. Early diagnosis of TB and rapid detection of drug resistance are important for the proper management of drug-resistant TB (DR-TB). Therefore, a laboratory based cross-sectional study was conducted from July to December 2019 at the National Tuberculosis Centre, Thimi, Nepal, with the objective of evaluating the diagnostic performance of Xpert MTB/RIF assay,

Indexed as

LPAMycobacterium tuberculosissensitivitysmear-negative specimensspecificityXpert MTB/RIF

Identifiers

PMID36278581
PMCPMC9624312

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.