Evidence map›Paper›PMID 36278549›Full record

ReviewJournal of developmental biology2022

Quantitative Experimental Embryology: A Modern Classical Approach.

Lara Busby, Dillan Saunders, Guillermo Serrano Nájera, Benjamin Steventon

Abstract readReview
In one paragraph

Review in Journal of developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Dynamical systems of fate and form in development.Seminars in cell & developmental biology · 2025
    Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lara BusbyDepartment of Genetics, University of Cambridge, Cambridge CB2 3EH, UK.
Dillan SaundersDepartment of Genetics, University of Cambridge, Cambridge CB2 3EH, UK.
Guillermo Serrano NájeraDepartment of Genetics, University of Cambridge, Cambridge CB2 3EH, UK.
Benjamin SteventonDepartment of Genetics, University of Cambridge, Cambridge CB2 3EH, UK.ORCID 0000-0001-7838-839X

Funding

Leverhulme Trust RG93881Wellcome TrustWellcome Trust 220022/Z/19/Z
6 · The paper itself

Abstract

Experimental Embryology is often referred to as a classical approach of developmental biology that has been to some extent replaced by the introduction of molecular biology and genetic techniques to the field. Inspired by the combination of this approach with advanced techniques to uncover core principles of neural crest development by the laboratory of Roberto Mayor, we review key quantitative examples of experimental embryology from recent work in a broad range of developmental biology questions. We propose that quantitative experimental embryology offers essential ways to explore the reaction of cells and tissues to targeted cell addition, removal, and confinement. In doing so, it is an essential methodology to uncover principles of development that remain elusive such as pattern regulation, scaling, and self-organisation.

Indexed as

inductionmechanicsregulationscaling

Identifiers

PMID36278549
PMCPMC9624316

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.