ArticleClocks & sleep2022
The Impact of Missing Data and Imputation Methods on the Analysis of 24-Hour Activity Patterns.
Article in Clocks & sleep, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- AI-Driven Mental Health Support for Caregivers of Individuals With Alzheimer Disease: Systematic Literature Review and Development of a Conceptual Framework.JMIR mental health · 2026Pooled it
- Accelerometer-Derived Relative Amplitude and Midlife Cognition: A Cross-Sectional Study.medRxiv : the preprint server for health sciences · 2026Article
- Unstable sleep and rest-activity rhythms in adolescents at-risk for bipolar disorder: Links to mood symptoms and the effect of sleep stabilization.Journal of affective disorders · 2026Article
- Circadian Regulation and Pain: A Systematic Review of the Association Between Rest-Activity Rhythm and Pain-Related Outcomes.Clocks & sleep · 2026Review
- Circadian Rest-Activity Rhythms, Cognition, and Alzheimer Disease Dementia in Adults With Down Syndrome.Neurology · 2026Article
- Determining a Likely Mechanism of Missingness in Repeated Measures Sleep Data From Wearable Fitness Trackers: Longitudinal Analysis.JMIR mHealth and uHealth · 2026Article
- Circadian Phase Estimation From Ambulatory Wearables With Particle Filtering: Accuracy Depends on Initialization, Recording Duration, and Light Exposure.Journal of biological rhythms · 2026Article
- Reliability of Actigraphy for the Assessment of Sleep and Circadian Rhythms in Rett and Related Syndromes.Journal of intellectual disability research : JIDR · 2026Article
- Rest-Activity Rhythms and Suicidal Ideation in Pediatric Bipolar Disorder.Bipolar disorders · 2026Article
- Using objective measures to evaluate the role of physical activity as a compensatory mechanism of emotion regulation.Journal of behavioral medicine · 2025Article
- Synergizing High-Quality Tourism Development and Digital Economy: A Coupling Coordination Analysis in Chinese Prefecture-Level Cities.Entropy (Basel, Switzerland) · 2025Article
- Article
- The Ecology of Human Sleep (EcoSleep) Cohort Study: Protocol for a longitudinal repeated measurement burst design study to assess the relationship between sleep determinants and outcomes under real-world conditions across time of year.Journal of sleep research · 2025Article
- Augmenting Circadian Biology Research With Data Science.Journal of biological rhythms · 2025Review
- A systematic review and meta-analysis of the first decade of compositional data analyses of 24-hour movement behaviours, health, and well-being in school-aged children.Journal of activity, sedentary and sleep behaviors · 2025Article
- Reliable measures of rest-activity rhythm fragmentation: how many days are needed?European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2024Article
- Mitigating data quality challenges in ambulatory wrist-worn wearable monitoring through analytical and practical approaches.Scientific reports · 2024Article
- Research on a machine learning-based adaptive and efficient screening model for psychological symptoms of community correctional prisoners.Scientific reports · 2024Article
- Impaired 24-h activity patterns are associated with an increased risk of Alzheimer's disease, Parkinson's disease, and cognitive decline.Alzheimer's research & therapy · 2024Article
- Isolated REM sleep behavior disorder is associated with altered 24-h rest-activity measures.Frontiers in sleep · 2023Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
The purpose of this study is to characterize the impact of the timing and duration of missing actigraphy data on interdaily stability (IS) and intradaily variability (IV) calculation. The performance of three missing data imputation methods (linear interpolation, mean time of day (ToD), and median ToD imputation) for estimating IV and IS was also tested. Week-long actigraphy records with no non-wear or missing timeseries data were masked with zeros or 'Not a Number' (NaN) across a range of timings and durations for single and multiple missing data bouts. IV and IS were calculated for true, masked, and imputed (i.e., linear interpolation, mean ToD and, median ToD imputation) timeseries data and used to generate Bland-Alman plots for each condition. Heatmaps were used to analyze the impact of timings and durations of and between bouts. Simulated missing data produced deviations in IV and IS for longer durations, midday crossings, and during similar timing on consecutive days. Median ToD imputation produced the least deviation among the imputation methods. Median ToD imputation is recommended to recapitulate IV and IS under missing data conditions for less than 24 h.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.