Evidence map›Paper›PMID 36278444›Full record

ArticleCurrent neurovascular research2022

Higher NT-proBNP Levels are Related to Poor Functional Outcome and Pneumonia in Acute Intracerebral Hemorrhage Patients.

Xinjia Pan, Huan Wu, Yi Zhou, Liyan Song, Wanqing Zhai, Shoujiang You, Weidong Hu, Yongjun Cao

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Article in Current neurovascular research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed, 1 citations in OpenAlex.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Xinjia PanDepartment of Neurology, The First People's Hospital of Taicang, Suzhou 215400, China.
Huan WuDepartment of Neurology, Suzhou Clinical Research Center of Neurological Disease, The Second Affiliated Hospital of Soochow University, Suzhou 215004, China.
Yi ZhouDepartment of Neurology, The First People's Hospital of Taicang, Suzhou 215400, China.
Liyan SongDepartment of Neurology, The First People's Hospital of Taicang, Suzhou 215400, China.
Wanqing ZhaiDepartment of Neurology, The First People's Hospital of Taicang, Suzhou 215400, China.
Shoujiang YouDepartment of Neurology, Suzhou Clinical Research Center of Neurological Disease, The Second Affiliated Hospital of Soochow University, Suzhou 215004, China.
Weidong HuDepartment of Neurology, Suzhou Clinical Research Center of Neurological Disease, The Second Affiliated Hospital of Soochow University, Suzhou 215004, China.
Yongjun CaoDepartment of Neurology, Suzhou Clinical Research Center of Neurological Disease, The Second Affiliated Hospital of Soochow University, Suzhou 215004, China.
Taizhou First People's Hospital · CNSecond Affiliated Hospital of Soochow University · CNSoochow University · CN

Funding

Discipline Construction Program of the Second Affiliated Hospital of Soochow University XKTJ-XK202001, XKTJ-TD202004Gusu Health Talents Program GSWS2020029National Natural Science Foundation of China 81901198, 82171296Suzhou Technology Development Programme SLT201924
6 · The paper itself

Abstract

backgroundWe investigated the association between N-Terminal Pro-B-Type Natriuretic Peptide (NT-proBNP) levels upon hospital admission and early hematoma growth (HG), inhospital pneumonia and major disability in patients with acute intracerebral hemorrhage (ICH).

methodsA total of 353 ICH patients from January 2014 to February 2019 were included in the present study. Patients were divided into three groups based on the admission NT-proBNP levels (T1: <61; T2: 61-199; T3: ≥199 pg/mL). Logistic regression models were used to estimate the effect of NT-proBNP on early HG, in-hospital pneumonia, and major disability upon hospital discharge (modified Rankin Scale score ≥5) in ICH patients.

resultsThere was no significant association observed between baseline NT-proBNP levels and early HG (P-trend =0.249). The risk of in-hospital pneumonia was significantly higher in patients with the highest NT-proBNP level (T3) (adjusted odds ratio [OR] 2.13; 95% confidence interval [CI], 1.11-4.08) and higher NT-proBNP level (T2) (adjusted OR 2.18; 95% CI, 1.19-4.00) compared to those with lowest NT-proBNP level (T1). The highest NT-proBNP level (T3) was associated with a 3.55-fold increase in the risk of major disability at hospital discharge (adjusted OR 3.55; 95% CI, 1.23-10.26; P-trend =0.013) in comparison to T1 after adjustment for potential covariates, including pneumonia.

conclusionIncreased NT-proBNP at admission was independently associated with in-hospital pneumonia and major disability upon discharge but not early hematoma growth in acute ICH patients.

Indexed as

Acute intracerebral hemorrhageischemic stroke.major disabilityNT-proBNPpneumoniaWBC

Identifiers

PMID36278444
OpenAlexW4306974299

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.