Evidence map›Paper›PMID 36278223›Full record

ArticleFrontiers in pharmacology2022

Calycosin attenuates renal ischemia/reperfusion injury by suppressing NF-κB mediated inflammation

Ningxin Zhang, Chen Guan, Zengying Liu, Chenyu Li, Chengyu Yang, Lingyu Xu, Meng Niu, Long Zhao, Bin Zhou, Lin Che and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
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  7. Study on the mechanism ofAnnals of medicine · 2025
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  12. Observational
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  15. Counteracting Alzheimer's diseaseActa pharmaceutica Sinica. B · 2024
    Article
  16. Calycosin inhibited MIF-mediated inflammatory chemotaxis of macrophages to ameliorate ischemia reperfusion-induced acute kidney injury.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024
    Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Ningxin ZhangDepartment of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Chen GuanDepartment of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Zengying LiuDepartment of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Chenyu LiDepartment of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Chengyu YangDepartment of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Lingyu XuDepartment of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Meng NiuDepartment of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Long ZhaoDepartment of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Bin ZhouDepartment of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Lin CheDepartment of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Yanfei WangDepartment of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Yan XuDepartment of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Affiliated Hospital of Qingdao University · CNQingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Renal ischemia reperfusion injury (IRI) is a leading and common cause of acute kidney injury (AKI), and inflammation is a critical factor in ischemic AKI progression. Calycosin (CAL), a major active component of

Indexed as

acute kidney injurycalycosinearly growth response 1ischemia/reperfusion injuryperoxisome proliferator-activated receptor γ

Identifiers

PMID36278223
PMCPMC9585199
OpenAlexW4303022563

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.