Evidence map›Paper›PMID 36278188›Full record

ReviewFrontiers in pharmacology2022

Newly discovered circRNAs in rheumatoid arthritis, with special emphasis on functional roles in inflammatory immunity.

Zhenyu Li, Jianpeng Wang, Yudong Lin, Jihong Fang, Kang Xie, Zhiye Guan, Hailong Ma, Liang Yuan

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Circular RNAs in Immune-Related Diseases.Advances in experimental medicine and biology · 2025
    Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Zhenyu LiWannan Medical College, Wuhu, China.
Jianpeng WangThe First Affiliated Hospital of Anhui Medical University, Anhui Medical University, Hefei, China.
Yudong LinDepartment of Pediatric Orthopedics, Anhui Provincial Children's Hospital, Hefei, China.
Jihong FangDepartment of Pediatric Orthopedics, Anhui Provincial Children's Hospital, Hefei, China.
Kang XieDepartment of Pediatric Orthopedics, Anhui Provincial Children's Hospital, Hefei, China.
Zhiye GuanDepartment of Pediatric Orthopedics, Anhui Provincial Children's Hospital, Hefei, China.
Hailong MaDepartment of Pediatric Orthopedics, Anhui Provincial Children's Hospital, Hefei, China.
Liang YuanDepartment of Pediatric Orthopedics, Anhui Provincial Children's Hospital, Hefei, China.
Anhui Provincial Children's Hospital · CNAnhui Medical University · CNWannan Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circular RNA (circRNA) is a unique type of endogenous RNA. It does not have free 3 'or 5' ends, but forms covalently closed continuous rings. Rheumatoid arthritis (RA) is a common chronic autoimmune joint disease, characterized by chronic inflammation of the joint synovial membrane, joint destruction, and the formation of pannus. Although the pathogenesis of rheumatoid arthritis remains incompletely understood, a growing amount of research shows that circRNA has a close relationship with RA. Researchers have found that abnormally expressed circRNAs may be associated with the occurrence and development of RA. This article reviews the inflammatory immune, functions, mechanisms, and values of the circRNAs in RA to provide new ideas and novel biomarkers for the diagnosis and treatment of RA.

Indexed as

CircRNAsimmuneinflammatoryrarheumatoid arthritis

Identifiers

PMID36278188
PMCPMC9585171
OpenAlexW4303021208

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.