Evidence map›Paper›PMID 36278048›Full record

ArticleACS omega2022

Pegylated Curcumin Derivative: Water-Soluble Conjugates with Antitumor and Antibacterial Activity.

Guldjan Yakub, Nevena E Manolova, Iliya B Rashkov, Nadya Markova, Reneta Toshkova, Ani Georgieva, Rosica Mincheva, Antoniya Toncheva, Jean-Marie Raquez, Philippe Dubois

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Chemical constituents in the rhizome of Curcuma longa and the pharmacological importance of curcumin hybrids.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2026
    Review
  2. Review
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  5. Synthesis, theoretical analysis, and biological properties of a novel tridentate Schiff base palladium (II) complex.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024
    Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Guldjan YakubLaboratory of Bioactive Polymers, Institute of Polymers, Bulgarian Academy of Sciences, Acad. G. Bonchev St, Bl. 103A, BG-1113Sofia, Bulgaria.
Nevena E ManolovaLaboratory of Bioactive Polymers, Institute of Polymers, Bulgarian Academy of Sciences, Acad. G. Bonchev St, Bl. 103A, BG-1113Sofia, Bulgaria.
Iliya B RashkovLaboratory of Bioactive Polymers, Institute of Polymers, Bulgarian Academy of Sciences, Acad. G. Bonchev St, Bl. 103A, BG-1113Sofia, Bulgaria.
Nadya MarkovaInstitute of Microbiology, Bulgarian Academy of Sciences, Acad. G. Bonchev St, bl. 26, BG-1113Sofia, Bulgaria.
Reneta ToshkovaInstitute of Experimental Morphology, Pathology and Anthropology with Museum, Bulgarian Academy of Sciences, Acad. G. Bonchev St, bl. 25, 1113Sofia, Bulgaria.
Ani GeorgievaInstitute of Experimental Morphology, Pathology and Anthropology with Museum, Bulgarian Academy of Sciences, Acad. G. Bonchev St, bl. 25, 1113Sofia, Bulgaria.
Rosica MinchevaService des Matériaux Polymères et Composites (SMPC), Université de Mons, Place du Parc 20, B7000Mons, Belgium.ORCID https://orcid.org/0000-0002-0479-9978
Antoniya TonchevaService des Matériaux Polymères et Composites (SMPC), Université de Mons, Place du Parc 20, B7000Mons, Belgium.
Jean-Marie RaquezService des Matériaux Polymères et Composites (SMPC), Université de Mons, Place du Parc 20, B7000Mons, Belgium.ORCID https://orcid.org/0000-0003-1940-7129
Philippe DuboisService des Matériaux Polymères et Composites (SMPC), Université de Mons, Place du Parc 20, B7000Mons, Belgium.
Bulgarian Academy of Sciences · BGUniversity of Mons · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the past years, the synthesis of polymer prodrug structures, based on natural phytochemical compounds with a great range of valuable biological properties, has become a promising solution in cancer prevention, imaging, and detection. Curcumin (Curc) remains one of the most studied natural products, due to the impressive palette of biological properties and the possibility to be easily loaded in various micro- and nanostructures and chemically modified. In this study, pegylated curcumin derivatives were prepared by a direct esterification reaction between poly(ethylene glycol)diacid (PEG of 600 g/mol molar mass, PEG

Identifiers

PMID36278048
PMCPMC9583079
OpenAlexW4303858869

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.