Evidence map›Paper›PMID 36277984›Full record

Trial reportDisease markers2022

Clinical Application of Anlotinib Combined with Docetaxel: Safe and Effective Treatment for Lung Carcinoma.

Xiang Ji, Xin Jing, Yongshi Liu, Jiangbo Huang, Sanhu Yang, Yuhui Yun

RetractedOpen access · hybridAbstract readRandomized Controlled TrialRetracted Publication
In one paragraph

Trial report in Disease markers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Xiang JiDepartment of Thoracic Surgery, Second Affiliated Hospital of Air Force Military Medical University, Xi'an, China.
Xin JingDepartment of Thoracic Surgery, Second Affiliated Hospital of Air Force Military Medical University, Xi'an, China.
Yongshi LiuDepartment of Thoracic Surgery, Second Affiliated Hospital of Air Force Military Medical University, Xi'an, China.
Jiangbo HuangEmergency Department, Trade Union Hospital of Xi'an, Xi'an, China.
Sanhu YangDepartment of Thoracic Surgery, Second Affiliated Hospital of Air Force Military Medical University, Xi'an, China.ORCID https://orcid.org/0000-0001-5413-263X
Yuhui YunDepartment of Thoracic Surgery, Second Affiliated Hospital of Air Force Military Medical University, Xi'an, China.ORCID https://orcid.org/0000-0002-8004-5393
Air Force Medical University · CNUnion Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To compare the clinical efficacy and long-term survival between anlotinib monotherapy and anlotinib plus docetaxel in patients with lung carcinoma. Methods: Between October 2019 and December 2021, 84 patients with lung cancer diagnosed and treated at our hospital were enrolled and randomly allocated to the control ( Results: There were no CR cases, 7 PR cases, 22 SD cases, and 13 PD cases in the control group. In the experimental group, there were 4 cases of CR, 20 cases of CR, 11 cases of SD, and 7 cases of PD. The overall clinical effectiveness of the experimental group was much higher than that of the control group. There were 3 cases of anemia, 5 cases of pyrexia, 6 cases of proteinuria, 9 cases of nausea and vomiting, and 4 cases of abnormal liver and renal function in the control group. ( Conclusion: Anlotinib combined with docetaxel is a safe and effective treatment for lung carcinoma to reduce the incidence of adverse reactions and improve the long-term survival rate. These benefits make it worthy of a broader clinical application. Although pharmacological treatment was applied in this study based on the mechanism, specific bioeffective markers are yet to be identified, presenting a direction for future research.

Indexed as

CarcinomaLung NeoplasmsDocetaxelFeverHumansIndolesLungNauseaProteinuriaQuinolinesTreatment OutcomeVomitinganlotinibDocetaxelIndolesQuinolines

Identifiers

PMID36277984
PMCPMC9586802
OpenAlexW4306248790

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.