Evidence map›Paper›PMID 36277935›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering

Calcium scoring in low-dose ungated chest CT scans using convolutional long-short term memory networks.

K Pieszko, A Shanbhag, A Killekar, M Lemley, Y Otaki, Serge Van Kriekinge, Paul Kavanagh, Robert Jh Miller, Edward J Miller, Tim Bateman and 3 more

Abstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
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  6. Article
  7. Deep Learning Coronary Artery Calcium Scores from SPECT/CT Attenuation Maps Improve Prediction of Major Adverse Cardiac Events.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

K PieszkoDepartments of Imaging and Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
A ShanbhagDepartments of Imaging and Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
A KillekarDepartments of Imaging and Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
M LemleyDepartments of Imaging and Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Y OtakiDepartments of Imaging and Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Serge Van KriekingeDepartments of Imaging and Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Paul KavanaghDepartments of Imaging and Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Robert Jh MillerDepartments of Imaging and Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Edward J MillerSection of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA.
Tim BatemanCardiovascular Imaging Technologies LLC, Kansas City, MO, USA.
D DeyDepartments of Imaging and Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
D BermanDepartments of Imaging and Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
P SlomkaDepartments of Imaging and Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

Funding

Quantitative Prediction of Disease and Outcomes from Next Generation SPECT and CTR01HL089765 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI SLOMKA, PIOTR J · 2007 to 2021
$6.1M
NHLBI NIH HHS R01 HL089765
6 · The paper itself

Abstract

We aimed to develop a novel deep-learning based method for automatic coronary artery calcium (CAC) quantification in low-dose ungated computed tomography attenuation correction maps (CTAC). In this study, we used convolutional long-short -term memory deep neural network (conv-LSTM) to automatically derive coronary artery calcium score (CAC) from both standard CAC scans and low-dose ungated scans (CT-attenuation correction maps). We trained convLSTM to segment CAC using 9543 scans. A U-Net model was trained as a reference method. Both models were validated in the OrCaCs dataset (n=32) and in the held-out cohort (n=507) without prior coronary interventions who had CTAC standard CAC scan acquired contemporarily. Cohen's kappa coefficients and concordance matrices were used to assess agreement in four CAC score categories (very low: <10, low:10-100; moderate:101-400 and high >400). The median time to derive results on a central processing unit (CPU) was significantly shorter for the conv-LSTM model- 6.18s (inter quartile range [IQR]: 5.99, 6.3) than for UNet (10.1s, IQR: 9.82, 15.9s, p<0.0001). The memory consumption during training was much lower for our model (13.11Gb) in comparison with UNet (22.31 Gb). Conv-LSTM performed comparably to UNet in terms of agreement with expert annotations, but with significantly shorter inference times and lower memory consumption.

Indexed as

Convolutional LSTMCoronary calcium scoringdeep learningPET CTAC

Identifiers

PMID36277935
PMCPMC9585987

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.