Evidence map›Paper›PMID 36277913›Full record

SynthesisFrontiers in neurology2022

The prevalence and associated factors of dysphagia in Parkinson's disease: A systematic review and meta-analysis.

Siyuan Gong, Yan Gao, Jihong Liu, Jia Li, Xueqin Tang, Qian Ran, Rongzhu Tang, Chunlian Liao

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 3 pooled it
13.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 3 syntheses or guidelines pooled it, 54 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Pooled it
  4. Article
  5. Frailty in Parkinson's disease: time to integrate it into treatment decision-making?Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Review
  6. Review
  7. Article
  8. Article
  9. Respiratory-Swallow Training and Variable Practice in Parkinson's Disease: A Clinical Trial Pilot Study.Folia phoniatrica et logopaedica : official organ of the International Association of Logopedics and Phoniatrics (IALP) · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Observational
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Siyuan GongDepartment of Neurology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Yan GaoNursing Department, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Jihong LiuDepartment of Neurology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Jia LiDepartment of Neurology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Xueqin TangDepartment of Neurology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Qian RanEndocrinology Department, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Rongzhu TangDepartment of Neurology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Chunlian LiaoDepartment of Neurology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Chongqing Medical University · CNSecond Affiliated Hospital of Chongqing Medical University · CNDalian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The prevalence and associated factors of dysphagia in Parkinson's disease (PD) are different in studies conducted in different countries. The purpose of our systematic review and meta-analysis was to evaluate the prevalence of dysphagia in PD and to clarify its associated factors. Methods: Two researchers systematically searched PubMed, Embase, Web of Science, Cochrane Library, CNKI, Wanfang Database, SinoMed and VIP databases and manually searched references in the retrieved articles to identify potential research subjects. The last search was conducted on June 28, 2022. Finally, a total of 58 studies including 60 observations with 20,530 PD patients were included in our meta-analysis. Results: The meta-analysis estimated that the pooled prevalence rate of dysphagia in PD was 36.9% (95% CI: 30.7-43.6%) and instrumental examination showed a higher prevalence (57.3%, 95% CI: 44.3-69.1%). Oceania showed the highest prevalence of dysphagia in PD (56.3%) compared to Africa (39.5%), Asia (38.6%), Europe (36.1%) and America (28.9%). Dysphagia in PD was associated with older age, lower body mass index, longer disease duration, higher Hoehn and Yahr stage and levodopa equivalent daily dose, PIGD subtype, severe motor symptoms, drooling and higher levels of depression, and lower quality of life. Conclusions: In conclusion, our meta-analysis showed that dysphagia occurs in more than one-third of PD patients and was associated with several demographic characteristics and PD-related characteristics, motor symptoms, non-motor symptoms, as well as decreased quality of life. It deserves early screening, diagnosis, and treatment in clinical practice to prevent serious complications from dysphagia.

Indexed as

associated factorsdysphagiameta-analysisParkinson's diseaseprevalence

Identifiers

PMID36277913
PMCPMC9582284
OpenAlexW4302303826

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.