Evidence map›Paper›PMID 36277903›Full record

ArticleBioMed research international2022

Causal Roles of Sleep Duration in Osteoporosis and Cardiometabolic Diseases: A Mendelian Randomization Study.

Bin He, Xiaojun Chen, Hao Liu, Muzi Zhang, Baoshan Yin, Lifeng Yin, Zhengxue Quan, Yunsheng Ou, Mingqi Sun, Yong Zhu and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Bin HeDepartment of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.ORCID https://orcid.org/0000-0003-1187-9930
Xiaojun ChenDepartment of Orthopedics, The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, Sichuan, China.
Hao LiuDepartment of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Muzi ZhangDepartment of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Baoshan YinDepartment of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Lifeng YinDepartment of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Zhengxue QuanDepartment of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Yunsheng OuDepartment of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Mingqi SunDepartment of Orthopaedic Trauma, The Second Affiliated Hospital of Inner Mongolia Medical University, Huhhot, Inner Mongolia, China.
Yong ZhuDepartment of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.ORCID https://orcid.org/0000-0002-1130-5331
Hongwang CuiDepartment of Spine and Osteopathic Surgery, The First Affiliated Hospital of Hainan Medical University, Haikou, China.ORCID https://orcid.org/0000-0002-8293-3378

Funding

Medical Research Council MC_PC_17228Medical Research Council MC_QA137853
6 · The paper itself

Abstract

Sleep duration suggests some association with osteoporosis and cardiometabolic diseases, but it is unknown if these associations are causal or confounded. In this two-sample Mendelian randomization (MR) study, we included the largest genome-wide association studies (GWASs) associated with sleep duration and the outcome measures of osteoporosis and cardiometabolic diseases. Finally, 25 single nucleotide polymorphisms (SNPs) associated with short sleep duration and 7 SNPs associated with long sleep duration obtained the genome-wide significance (

Indexed as

Cardiovascular DiseasesCoronary Artery DiseaseDiabetes Mellitus, Type 2Heart FailureInsulinsOsteoporosisSleep Wake DisordersGenome-Wide Association StudyGlucoseGlycated HemoglobinHumansMendelian Randomization AnalysisPolymorphism, Single NucleotideSleepGlucoseGlycated HemoglobinInsulins

Identifiers

PMID36277903
PMCPMC9586149

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.