Evidence map›Paper›PMID 36277878›Full record

ArticleBioMed research international2022

Effects of Clopidogrel Rehabilitation on Cardiac Protein Kinase C, Cardiac Heat Shock Protein 70, and CI in MIRI Rat Model.

Qiaoyan Ma, Lizhong Wang, Hongyan Ma, Qian Cao, Jiagui Ma

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Qiaoyan MaBeijing Rehabilitation Hospital of Capital Medical University, Beijing 100144, China.
Lizhong WangBeijing Rehabilitation Hospital of Capital Medical University, Beijing 100144, China.ORCID https://orcid.org/0000-0002-7554-6126
Hongyan MaDongzhimen Hospital Beijing University of Chinese Medicine, Beijing 101121, China.
Qian CaoBeijing Rehabilitation Hospital of Capital Medical University, Beijing 100144, China.
Jiagui MaBeijing Rehabilitation Hospital of Capital Medical University, Beijing 100144, China.
Capital Medical University · CNDongzhimen Hospital Affiliated to Beijing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In order to investigate the effects of clopidogrel rehabilitation on the levels of cardiac protein kinase C (PKC), cardiac heat shock protein 70 (HSP70), and cardiac index (CI) in rats with myocardial ischemia-reperfusion injury (MIRI), sixty Wistar rats are randomly divided into three groups (sham operation group, model group, and clopidogrel group), with 20 rats in each group. The clopidogrel group is given clopidogrel by gavage, and the sham operation group and the model group are given the same amount of normal saline by gavage. The experimental results show that compared with the model group, the clopidogrel group has clear horizontal lines and cell edema. The myocardial infarction rate, creatine kinase-MB (CK-MB), and malondialdehyde (MDA) of the model group and clopidogrel group in the control sham operation group significantly increase.

Indexed as

Myocardial Reperfusion InjuryAnimalsClopidogrelCreatine KinaseHSP70 Heat-Shock ProteinsMalondialdehydeProtein Kinase CRatsRats, WistarClopidogrelCreatine KinaseHSP70 Heat-Shock ProteinsMalondialdehydeProtein Kinase C

Identifiers

PMID36277878
PMCPMC9584675
OpenAlexW4306152006

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.