Evidence map›Paper›PMID 36277726›Full record

ArticleFrontiers in endocrinology2022

Leptin and environmental temperature as determinants of bone marrow adiposity in female mice.

Russell T Turner, Kira L Nesser, Kenneth A Philbrick, Carmen P Wong, Dawn A Olson, Adam J Branscum, Urszula T Iwaniec

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Russell T TurnerSkeletal Biology Laboratory, School of Biological and Population Health Sciences, Oregon State University, Corvallis, OR, United States.
Kira L NesserSkeletal Biology Laboratory, School of Biological and Population Health Sciences, Oregon State University, Corvallis, OR, United States.
Kenneth A PhilbrickSkeletal Biology Laboratory, School of Biological and Population Health Sciences, Oregon State University, Corvallis, OR, United States.
Carmen P WongSkeletal Biology Laboratory, School of Biological and Population Health Sciences, Oregon State University, Corvallis, OR, United States.
Dawn A OlsonSkeletal Biology Laboratory, School of Biological and Population Health Sciences, Oregon State University, Corvallis, OR, United States.
Adam J BranscumBiostatistics Program, School of Biological and Population Health Sciences, Oregon State University, Corvallis, OR, United States.
Urszula T IwaniecSkeletal Biology Laboratory, School of Biological and Population Health Sciences, Oregon State University, Corvallis, OR, United States.
Oregon State University · US

Funding

The Role of Leptin in Inflammation-Driven Bone LossR01AR060913 · NIAMS · OREGON STATE UNIVERSITY · PI IWANIEC, URSZULA T · 2011 to 2025
$3.5M
NIAMS NIH HHS R01 AR060913
6 · The paper itself

Abstract

Bone marrow adipose tissue (BMAT) levels are higher in distal femur metaphysis of female mice housed at thermoneutral (32°C) than in mice housed at 22°C, as are abdominal white adipose tissue (WAT) mass, and serum leptin levels. We performed two experiments to explore the role of increased leptin in temperature-enhanced accrual of BMAT. First, we supplemented 6-week-old female C57BL/6J (B6) mice with leptin for 2 weeks at 10 µg/d using a subcutaneously implanted osmotic pump. Controls consisted of

Indexed as

Bone MarrowLeptinAdiposityAnimalsFemaleMiceMice, Inbred C57BLObesityTemperatureLeptinBMAThistomorphometryleptinmarrow adipose tissueroom temperaturethermoneutral

Identifiers

PMID36277726
PMCPMC9582271
OpenAlexW4303191025

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.