Evidence map›Paper›PMID 36277640›Full record

ArticleChemical science2022

Iron-catalysed alkene and heteroarene H/D exchange by reversible protonation of iron-hydride intermediates.

Luke Britton, Jamie H Docherty, Jan Sklyaruk, Jessica Cooney, Gary S Nichol, Andrew P Dominey, Stephen P Thomas

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Deuteration of Six-Membered N-Heteroarenes: Chemistry and Applications.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Review
  3. Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Luke BrittonEaStCHEM School of Chemistry, University of Edinburgh Edinburgh EH9 3FJ UK jamie.docherty@ed.ac.uk stephen.thomas@ed.ac.uk.
Jamie H DochertyEaStCHEM School of Chemistry, University of Edinburgh Edinburgh EH9 3FJ UK jamie.docherty@ed.ac.uk stephen.thomas@ed.ac.uk.ORCID https://orcid.org/0000-0001-5584-7530
Jan SklyarukEaStCHEM School of Chemistry, University of Edinburgh Edinburgh EH9 3FJ UK jamie.docherty@ed.ac.uk stephen.thomas@ed.ac.uk.
Jessica CooneyEaStCHEM School of Chemistry, University of Edinburgh Edinburgh EH9 3FJ UK jamie.docherty@ed.ac.uk stephen.thomas@ed.ac.uk.
Gary S NicholEaStCHEM School of Chemistry, University of Edinburgh Edinburgh EH9 3FJ UK jamie.docherty@ed.ac.uk stephen.thomas@ed.ac.uk.ORCID https://orcid.org/0000-0002-1597-3679
Andrew P DomineyGSK Medicines Research Centre Stevenage SG1 2NY UK.
Stephen P ThomasEaStCHEM School of Chemistry, University of Edinburgh Edinburgh EH9 3FJ UK jamie.docherty@ed.ac.uk stephen.thomas@ed.ac.uk.ORCID https://orcid.org/0000-0001-8614-2947
University of Edinburgh · GBAge UK · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

C-H functionalisation reactions offer a sustainable method for molecular construction and diversification. These reactions however remain dominated by precious metal catalysis. While significant interest in iron-catalysed C-H activation reactions has emerged, the isolation, characterisation and mechanistic understanding of these processes remain lacking. Herein the iron-catalysed C(sp

Identifiers

PMID36277640
PMCPMC9473494
OpenAlexW4290995166

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.