Evidence map›Paper›PMID 36277623›Full record

ArticleChemical science2022

Electrochemical oxidative rearrangement of tetrahydro-β-carbolines in a zero-gap flow cell.

Yiting Zheng, Yuen Tsz Cheung, Lixin Liang, Huiying Qiu, Lei Zhang, Anson Tsang, Qing Chen, Rongbiao Tong

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Yiting ZhengDepartment of Mechanical and Aerospace Engineering, and Energy Institute, The Hong Kong University of Science and Technology Clear Water Bay Kowloon Hong Kong P. R. China chenqing@ust.hk.
Yuen Tsz CheungDepartment of Chemistry, The Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou), The Hong Kong University of Science and Technology Clear Water Bay Kowloon Hong Kong SAR China rtong@ust.hk +852 23581594 +852 23587357.
Lixin LiangDepartment of Chemistry, The Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou), The Hong Kong University of Science and Technology Clear Water Bay Kowloon Hong Kong SAR China rtong@ust.hk +852 23581594 +852 23587357.ORCID https://orcid.org/0000-0003-1790-8472
Huiying QiuDepartment of Chemistry, The Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou), The Hong Kong University of Science and Technology Clear Water Bay Kowloon Hong Kong SAR China rtong@ust.hk +852 23581594 +852 23587357.
Lei ZhangState Key Laboratory of Electrical Insulation and Power Equipment, Xi'an Jiaotong University Xi'an 710049 China.
Anson TsangDepartment of Mechanical and Aerospace Engineering, and Energy Institute, The Hong Kong University of Science and Technology Clear Water Bay Kowloon Hong Kong P. R. China chenqing@ust.hk.
Qing ChenDepartment of Mechanical and Aerospace Engineering, and Energy Institute, The Hong Kong University of Science and Technology Clear Water Bay Kowloon Hong Kong P. R. China chenqing@ust.hk.ORCID https://orcid.org/0000-0003-3106-9281
Rongbiao TongDepartment of Chemistry, The Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou), The Hong Kong University of Science and Technology Clear Water Bay Kowloon Hong Kong SAR China rtong@ust.hk +852 23581594 +852 23587357.ORCID https://orcid.org/0000-0002-2740-5222
Hong Kong University of Science and Technology · HKXi'an Jiaotong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative rearrangement of tetrahydro-β-carbolines (THβCs) is one of the most efficient methods for the synthesis of biologically active spirooxindoles, including natural products and drug molecules. Here, we report the first electrochemical approach to achieve this important organic transformation in a flow cell. The key to the high efficiency was the use of a multifunctional LiBr electrolyte, where the bromide (Br

Identifiers

PMID36277623
PMCPMC9473527
OpenAlexW4293231881

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.