Evidence map›Paper›PMID 36277485›Full record

ArticleFrontiers in molecular neuroscience2022

Deficiency of miR-29a/b1 leads to premature aging and dopaminergic neuroprotection in mice.

Xiaochen Bai, Jinghui Wang, Xiaoshuang Zhang, Yilin Tang, Yongtao He, Jiayin Zhao, Linlin Han, Rong Fang, Zhaolin Liu, Hongtian Dong and 8 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in molecular neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 1 country.

Xiaochen BaiDepartment of Translational Neuroscience, MOE Frontiers Center for Brain Science, Institutes of Brain Science, State Key Laboratory of Medical Neurobiology, Jing'an District Centre Hospital of Shanghai, Fudan University, Shanghai, China.
Jinghui WangDepartment of Translational Neuroscience, MOE Frontiers Center for Brain Science, Institutes of Brain Science, State Key Laboratory of Medical Neurobiology, Jing'an District Centre Hospital of Shanghai, Fudan University, Shanghai, China.
Xiaoshuang ZhangDepartment of Translational Neuroscience, MOE Frontiers Center for Brain Science, Institutes of Brain Science, State Key Laboratory of Medical Neurobiology, Jing'an District Centre Hospital of Shanghai, Fudan University, Shanghai, China.
Yilin TangDepartment of Translational Neuroscience, MOE Frontiers Center for Brain Science, Institutes of Brain Science, State Key Laboratory of Medical Neurobiology, Jing'an District Centre Hospital of Shanghai, Fudan University, Shanghai, China.
Yongtao HeDepartment of Translational Neuroscience, MOE Frontiers Center for Brain Science, Institutes of Brain Science, State Key Laboratory of Medical Neurobiology, Jing'an District Centre Hospital of Shanghai, Fudan University, Shanghai, China.
Jiayin ZhaoDepartment of Translational Neuroscience, MOE Frontiers Center for Brain Science, Institutes of Brain Science, State Key Laboratory of Medical Neurobiology, Jing'an District Centre Hospital of Shanghai, Fudan University, Shanghai, China.
Linlin HanDepartment of Translational Neuroscience, MOE Frontiers Center for Brain Science, Institutes of Brain Science, State Key Laboratory of Medical Neurobiology, Jing'an District Centre Hospital of Shanghai, Fudan University, Shanghai, China.
Rong FangDepartment of Translational Neuroscience, MOE Frontiers Center for Brain Science, Institutes of Brain Science, State Key Laboratory of Medical Neurobiology, Jing'an District Centre Hospital of Shanghai, Fudan University, Shanghai, China.
Zhaolin LiuDepartment of Translational Neuroscience, MOE Frontiers Center for Brain Science, Institutes of Brain Science, State Key Laboratory of Medical Neurobiology, Jing'an District Centre Hospital of Shanghai, Fudan University, Shanghai, China.
Hongtian DongDepartment of Translational Neuroscience, MOE Frontiers Center for Brain Science, Institutes of Brain Science, State Key Laboratory of Medical Neurobiology, Jing'an District Centre Hospital of Shanghai, Fudan University, Shanghai, China.
Qing LiDepartment of Translational Neuroscience, MOE Frontiers Center for Brain Science, Institutes of Brain Science, State Key Laboratory of Medical Neurobiology, Jing'an District Centre Hospital of Shanghai, Fudan University, Shanghai, China.
Jingyu GeDepartment of Translational Neuroscience, MOE Frontiers Center for Brain Science, Institutes of Brain Science, State Key Laboratory of Medical Neurobiology, Jing'an District Centre Hospital of Shanghai, Fudan University, Shanghai, China.
Yuanyuan MaDepartment of Translational Neuroscience, MOE Frontiers Center for Brain Science, Institutes of Brain Science, State Key Laboratory of Medical Neurobiology, Jing'an District Centre Hospital of Shanghai, Fudan University, Shanghai, China.
Mei YuDepartment of Translational Neuroscience, MOE Frontiers Center for Brain Science, Institutes of Brain Science, State Key Laboratory of Medical Neurobiology, Jing'an District Centre Hospital of Shanghai, Fudan University, Shanghai, China.
Ruilin SunShanghai Engineering Research Center for Model Organisms, SMOC, Shanghai, China.
Jian WangDepartment of Translational Neuroscience, MOE Frontiers Center for Brain Science, Institutes of Brain Science, State Key Laboratory of Medical Neurobiology, Jing'an District Centre Hospital of Shanghai, Fudan University, Shanghai, China.
Jian FeiShanghai Engineering Research Center for Model Organisms, SMOC, Shanghai, China.
Fang HuangDepartment of Translational Neuroscience, MOE Frontiers Center for Brain Science, Institutes of Brain Science, State Key Laboratory of Medical Neurobiology, Jing'an District Centre Hospital of Shanghai, Fudan University, Shanghai, China.
Fudan University · CNTongji University · CNShanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parkinson's disease (PD) is a neurodegenerative disorder characterized by progressive degeneration of midbrain dopaminergic neurons. The miR-29s family, including

Indexed as

AMPKglial cellsmiR-29a/b1neuroinflammationParkinson’s disease

Identifiers

PMID36277485
PMCPMC9582353
OpenAlexW4302303871

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.