Evidence map›Paper›PMID 36277299›Full record

ArticleTherapeutic advances in infectious disease

Seasonal variations and risk factors of

Matthew Kennis, Alex Tagawa, Vanessa M Kung, Gabrielle Montalbano, Isabella Narvaez, Carlos Franco-Paredes, Lilian Vargas Barahona, Nancy Madinger, Leland Shapiro, Daniel B Chastain and 1 more

Open access · goldAbstract read
In one paragraph

Article in Therapeutic advances in infectious disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 16 citations in OpenAlex.

  1. Genomic analysis and clinical characteristics of a seasonal upsurge of Streptococcus pyogenes emm12.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Trends in Group AMedicina (Kaunas, Lithuania) · 2025
    Observational
  6. Post-pandemic upsurge in Group AMicrobiology spectrum · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Spatiotemporal Trends in Group A Streptococcal Pharyngitis in the United States.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Article
  11. Epidemiology and emm types among group A streptococcal pharyngitis in Finland: a prospective laboratory-based study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Article
  12. Article
  13. Review
  14. Article
  15. Spatiotemporal Trends in Group A Streptococcal Pharyngitis in the United States.medRxiv : the preprint server for health sciences · 2023
    Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Matthew KennisDivision of Infectious Diseases, School of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, CO, USA.
Alex TagawaCenter for Gait and Movement Analysis (CGMA), Children's Hospital Colorado, Aurora, CO, USA.
Vanessa M KungDivision of Infectious Diseases, School of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, CO, USA.
Gabrielle MontalbanoDivision of Infectious Diseases, School of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, CO, USA.
Isabella NarvaezDivision of Infectious Diseases, School of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, CO, USA.
Carlos Franco-ParedesHospital Infantil de México, Federico Gómez, México City, México.
Lilian Vargas BarahonaDivision of Infectious Diseases, School of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, CO, USA.ORCID https://orcid.org/0000-0003-3330-808X
Nancy MadingerDivision of Infectious Diseases, School of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, CO, USA.
Leland ShapiroDivision of Infectious Diseases, School of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, CO, USA.
Daniel B ChastainDepartment of Clinical and Administrative Pharmacy, University of Georgia College of Pharmacy, Albany, GA, USA.ORCID https://orcid.org/0000-0002-4018-0195
Andrés F Henao-MartínezDivision of Infectious Diseases, School of Medicine, University of Colorado Anschutz Medical Campus, 12700 E. 19th Avenue, Mail Stop B168, Aurora, CO 80045, USA.ORCID https://orcid.org/0000-0001-7363-8652
University of Colorado Anschutz Medical Campus · USChildren's Hospital Colorado · USGeorgia College & State University · USHospital Infantil de México Federico Gómez · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: From the period 2010-2019, we conducted a case-control study using laboratory-confirmed cases of GAS pharyngitis and a descriptive observational study of necrotizing fasciitis using ICD-10 codes. Data were collected from TriNetX, a federated research network. We extracted seasonal (quarterly) incidence rates. We used an autoregressive integrated moving average (ARIMA) model to assess seasonal variations. Demographic characteristics and 1-month outcomes were compared among adults with or without GAS pharyngitis. Results: We identified 224,471 adults with GAS pharyngitis (test-positive) and 546,142 adults without it (test-negative). GAS pharyngitis adults were younger (25.3 Conclusion: Peaks in GAS pharyngitis occur in the winter months. ICD code-based necrotizing fasciitis did not show a quarterly seasonal variation.

Indexed as

group A streptococcusnecrotizing fasciitispharyngitisseasonal variationStreptococcus pyogenes

Identifiers

PMID36277299
PMCPMC9585558
OpenAlexW4307234587

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.