Evidence map›Paper›PMID 36277272›Full record

ArticleJournal of central nervous system disease2022

Central nervous system, spinal root ganglion and brachial plexus involvement in leprosy: A prospective study.

Sumit Verma, Ravindra Kumar Garg, Imran Rizvi, Hardeep Singh Malhotra, Neeraj Kumar, Amita Jain, Swastika Suvirya, Anit Parihar, Rajesh Verma, Praveen Kumar Sharma and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of central nervous system disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Observational
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Sumit VermaDepartment of Neurology, King George Medical University, Uttar Pradesh, Lucknow, India.
Ravindra Kumar GargDepartment of Neurology, King George Medical University, Uttar Pradesh, Lucknow, India.ORCID https://orcid.org/0000-0003-0044-7083
Imran RizviDepartment of Neurology, King George Medical University, Uttar Pradesh, Lucknow, India.
Hardeep Singh MalhotraDepartment of Neurology, King George Medical University, Uttar Pradesh, Lucknow, India.ORCID https://orcid.org/0000-0003-0438-4446
Neeraj KumarDepartment of Neurology, King George Medical University, Uttar Pradesh, Lucknow, India.
Amita JainDepartment of Microbiology, King George Medical University, Uttar Pradesh, Lucknow, India.
Swastika SuviryaDepartment of Dermatology, King George Medical University, Uttar Pradesh, Lucknow, India.
Anit PariharDepartment of Radiodiagnosis, King George Medical University, Uttar Pradesh, Lucknow, India.
Rajesh VermaDepartment of Neurology, King George Medical University, Uttar Pradesh, Lucknow, India.
Praveen Kumar SharmaDepartment of Neurology, King George Medical University, Uttar Pradesh, Lucknow, India.
Shweta PandeyDepartment of Neurology, King George Medical University, Uttar Pradesh, Lucknow, India.
Ravi UniyalDepartment of Neurology, King George Medical University, Uttar Pradesh, Lucknow, India.
Shantanu PrakashDepartment of Microbiology, King George Medical University, Uttar Pradesh, Lucknow, India.
King George's Medical University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Leprosy is primarily a disease of peripheral nerves. Some isolated case reports and case series have communicated imaging changes in the central nervous system (CNS) and brachial plexus in patients with leprosy. Objectives: To study the neuroimaging abnormalities in patients with lepra bacilli-positive neuropathy in the context of CNS, spinal root ganglion, and brachial plexus. Design: Prospective observational study. Methods: We screened newly-diagnosed patients with multibacillary leprosy presenting with neuropathy. Patients with bacilli-positive sural nerve biopsies were included in the study and subjected to magnetic resonance imaging (MRI) of the brain and spinal cord. Results: A total of 54 patients with bacteriologically confirmed multibacillary leprosy were screened; Conclusion: CNS, spinal root ganglion, and brachial plexus are involved in patients with leprous neuropathy. Immunological reaction against

Indexed as

BrainbrainstemHansen’s diseaseMycobacterium lepraemyelitisspinal cord

Identifiers

PMID36277272
PMCPMC9583215
OpenAlexW4307229217

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.