Evidence map›Paper›PMID 36277242›Full record

ReviewInfection and drug resistance2022

Quality of Antimalarial Drugs in East Africa: A Systematic Review.

Million Girma, Belachew Umeta, Gemmechu Hasen, Sultan Suleman

Abstract readReview
In one paragraph

Review in Infection and drug resistance, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Million GirmaSchool of Pharmacy, College of Medicine and Health Sciences, Wolaita Sodo University, Wolaita Sodo, Ethiopia.
Belachew UmetaSchool of Pharmacy, Institute of Health, Jimma University, Jimma, Ethiopia.ORCID 0000-0002-8420-2253
Gemmechu HasenSchool of Pharmacy, Institute of Health, Jimma University, Jimma, Ethiopia.ORCID 0000-0002-1693-0240
Sultan SulemanSchool of Pharmacy, Institute of Health, Jimma University, Jimma, Ethiopia.ORCID 0000-0003-3046-6760

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The use of poor quality drugs will have multiple consequences with an extended hazard of growing drug-resistant strains. Purpose: The review aimed to provide the quality status of antimalarial drugs in East Africa. Data Source: PubMed, Scopus, Web of Science, and Google Scholar were searched from September 5 to September 12, 2021. Study Selection: The review included articles available as original research targeted at evaluating the quality of antimalarial drugs. For inclusion, data on at least one of the following quality control parameters were required: packaging and labeling, hardness, friability, weight variation/uniformity of weight, disintegration, dissolution, and assay/percentage purity. Mendeley citation manager version 1.19.4 was used to avoid duplication and organize references, and titles and abstracts were primarily used for screening. Data Extraction: The sample collection site, drug name, and the quality control parameters tested were retrieved from the selected studies. Data synthesis: Conclusions: An unneglected amount of antimalarial drug failed to meet at least one quality control parameter. Strengthening pharmaceutical management systems, including post-marketing surveillance, and providing the resources required for medication quality assurance, are recommended.

Indexed as

antimalarial drugsartemether/lumefantrineassaycoartemdissolutionEast Africaquality control

Identifiers

PMID36277242
PMCPMC9585264

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.