Evidence map›Paper›PMID 36277179›Full record

ArticleFrontiers in physiology2022

Exogenous detection of

Amandine Verlande, Sung Kook Chun, Wei A Song, Daniela Oettler, Harm J Knot, Selma Masri

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Amandine VerlandeDepartment of Biological Chemistry, University of California, Irvine, Irvine, CA, United States.
Sung Kook ChunDepartment of Biological Chemistry, University of California, Irvine, Irvine, CA, United States.
Wei A SongDepartment of Biological Chemistry, University of California, Irvine, Irvine, CA, United States.
Daniela OettlerTSE Systems Inc., Chesterfield, MO, United States.
Harm J KnotTSE Systems Inc., Chesterfield, MO, United States.
Selma MasriDepartment of Biological Chemistry, University of California, Irvine, Irvine, CA, United States.
University of California, Irvine · US

Funding

Univ.of Calif., Irvine Cancer Center Support GrantP30CA062203 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Melanie Funes · 1994 to 2026
$57.9M
Circadian Clock and Myc-dependent Regulation of Cellular TransformationR01CA259370 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Selma Masri · 2022 to 2026
$3.0M
Circadian Clock Disruption and Colorectal CancerR01CA244519 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Selma Masri · 2020 to 2026
$3.0M
Tumor Macroenvironment and the Circadian Metabolic ClockK22CA212045 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI MASRI, SELMA · 2018 to 2020
$607k
NCI NIH HHS K22 CA212045NCI NIH HHS P30 CA062203NCI NIH HHS R01 CA244519NCI NIH HHS R01 CA259370
6 · The paper itself

Abstract

Metabolic rewiring is a hallmark feature prevalent in cancer cells as well as insulin resistance (IR) associated with diet-induced obesity (DIO). For instance, tumor metabolism shifts towards an enhanced glycolytic state even under aerobic conditions. In contrast, DIO triggers lipid-induced IR by impairing insulin signaling and reducing insulin-stimulated glucose uptake. Based on physiological differences in systemic metabolism, we used a breath analysis approach to discriminate between different pathological states using glucose oxidation as a readout. We assessed glucose utilization in lung cancer-induced cachexia and DIO mouse models using a U-

Indexed as

circadian clockdiet-induced obesity (DIO)glucose oxidation and detectioninsulin resistancetumor metabolism

Identifiers

PMID36277179
PMCPMC9581140
OpenAlexW4301585506

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.