Evidence map›Paper›PMID 36277112›Full record

ArticleOne health (Amsterdam, Netherlands)2022

Novel variant Hendra virus genotype 2 infection in a horse in the greater Newcastle region, New South Wales, Australia.

Joanne Taylor, Kirrilly Thompson, Edward J Annand, Peter D Massey, Jane Bennett, John-Sebastian Eden, Bethany A Horsburgh, Evelyn Hodgson, Kelly Wood, James Kerr and 5 more

Abstract read
In one paragraph

Article in One health (Amsterdam, Netherlands), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Joanne TaylorHunter New England Local Health District, Wallsend 2287, Australia.
Kirrilly ThompsonHunter New England Local Health District, Wallsend 2287, Australia.
Edward J AnnandUniversity of Sydney, Sydney Institute for Infectious Diseases & Sydney School of Veterinary Science, Sydney 2006, Australia.
Peter D MasseyHunter New England Local Health District, Wallsend 2287, Australia.
Jane BennettNew South Wales Department of Primary Industries, Orange 2800, Australia.
John-Sebastian EdenUniversity of Sydney, Sydney Institute for Infectious Diseases & Sydney School of Veterinary Science, Sydney 2006, Australia.
Bethany A HorsburghUniversity of Sydney, Sydney Institute for Infectious Diseases & Sydney School of Veterinary Science, Sydney 2006, Australia.
Evelyn HodgsonNewcastle Equine Centre, Broadmeadow 2292, Australia.
Kelly WoodNew South Wales Department of Primary Industries, Orange 2800, Australia.
James KerrHunter Local Land Services, Tocal 2421, Australia.
Peter KirklandElizabeth Macarthur Agricultural Institute, Menangle 2568, Australia.
Deborah FinlaisonElizabeth Macarthur Agricultural Institute, Menangle 2568, Australia.
Alison J PeelGriffith University, Centre for Planetary Health and Food Security, Nathan 4111, Australia.
Peggy EbyGriffith University, Centre for Planetary Health and Food Security, Nathan 4111, Australia.
David N DurrheimHunter New England Local Health District, Wallsend 2287, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In October 2021, the first contemporary detection of Hendra virus genotype 2 (HeV-g2) was made by veterinary priority disease investigation in a horse near Newcastle, New South Wales, Australia, as part of routine veterinary priority disease surveillance. This discovery followed an update of Hendra virus diagnostic assays following retrospective identification of this variant from 2015 via sentinel emerging infectious disease research, enabling timely detection of this case. The sole infected horse was euthanized in moribund condition. As the southernmost recognised HeV spill-over detection to date, it extends the southern limit of known cases by approximately 95 km. The event occurred near a large urban centre, characterised by equine populations of diverse type, husbandry, and purpose, with low HeV vaccination rates. Urgent multi-agency outbreak response involved risk assessment and monitoring of 11 exposed people and biosecurity management of at-risk animals. No human or additional animal cases were recognised. This One Health investigation highlights need for research on risk perception and strategic engagement to support owners confronted with the death of companion animals and potential human exposure to a high consequence virus. The location and timing of this spill-over event diverging from that established for prototype HeV (HeV-g1), highlight benefit in proactive One Health surveillance and research activities that improve understanding of dynamic transmission and spill-over risks of both HeV genotypic lineages and related but divergent emerging pathogens.

Identifiers

PMID36277112
PMCPMC9582560

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.