Evidence map›Paper›PMID 36276996›Full record

ReviewComputational and mathematical methods in medicine2022

The Expressions and Functions of lncRNA Related to m6A in Hepatocellular Carcinoma from a Bioinformatics Analysis.

Shengwei Du, Ying Guo, Jian Huang, Jiajia Xu, Guorong Chen

Open access · hybridAbstract readReview
In one paragraph

Review in Computational and mathematical methods in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Shengwei DuThe First Affiliated Hospital, Wenzhou Medical University, Wenzhou, China.ORCID https://orcid.org/0000-0003-1878-124X
Ying GuoThe First Affiliated Hospital, Wenzhou Medical University, Wenzhou, China.ORCID https://orcid.org/0000-0001-5786-1563
Jian HuangThe First Affiliated Hospital, Wenzhou Medical University, Wenzhou, China.ORCID https://orcid.org/0000-0002-4098-9197
Jiajia XuThe First Affiliated Hospital, Wenzhou Medical University, Wenzhou, China.ORCID https://orcid.org/0000-0002-6293-4664
Guorong ChenThe First Affiliated Hospital, Wenzhou Medical University, Wenzhou, China.ORCID https://orcid.org/0000-0002-9966-6691
Wenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is one of the most common cancer in these days. Besides, N6-methyladenosine (m6A) plays an important role in the occurrence and development of hepatocellular carcinoma. Meanwhile, it is known to us that long noncoding RNAs (lncRNA) have the capability to control the expression of genes which means some lncRNA can adjust the expression of some m6A.Thus, it is indispensable to dig the m6A-related lncRNA in hepatocellular carcinoma about its potential regulatory mechanism and immune analysis as well as its potential drugs. In this experiment, expression profile and clinical information of lncRNA are obtained by downloading the liver cancer data set from The Cancer Genome Atlas (TCGA) database. GO enrichment analysis is used to predict potential regulatory mechanism of lncRNA. Correlation analysis of clinical parameters are calculated via chisq.test. The Cox regression model is used in univariate and multivariate analysis, and the difference is statistically significant when

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsRNA, Long NoncodingComputational BiologyGene Expression Regulation, NeoplasticHumansPrognosisRNA, Long Noncoding

Identifiers

PMID36276996
PMCPMC9581679
OpenAlexW4304842808

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.