Evidence map›Paper›PMID 36276647›Full record

ArticleTheranostics2022

Targeting PI4KA sensitizes refractory leukemia to chemotherapy by modulating the ERK/AMPK/OXPHOS axis.

Xiuxing Jiang, Xiangtao Huang, Guoxun Zheng, Guanfei Jia, Zhiqiang Li, Xin Ding, Ling Lei, Liang Yuan, Shuangnian Xu, Ning Gao

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. AlphaFold3: A Transformer in Life Sciences.Current medicinal chemistry · 2026
    Review
  3. Review
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Xiuxing JiangCollege of Pharmacy, Army Medical University, 30 Gaotanyan Street, Shapingba District, Chongqing 400038, China.
Xiangtao HuangDepartment of Hematology, Southwest Hospital, Army Medical University, Chongqing 400038, China.
Guoxun ZhengShanghai StoneWise AI Technology Co. Ltd. Shanghai 201210, China.
Guanfei JiaCollege of Pharmacy, Army Medical University, 30 Gaotanyan Street, Shapingba District, Chongqing 400038, China.
Zhiqiang LiCollege of Pharmacy, Army Medical University, 30 Gaotanyan Street, Shapingba District, Chongqing 400038, China.
Xin DingCollege of Pharmacy, Army Medical University, 30 Gaotanyan Street, Shapingba District, Chongqing 400038, China.
Ling LeiCollege of Pharmacy, Army Medical University, 30 Gaotanyan Street, Shapingba District, Chongqing 400038, China.
Liang YuanKey Laboratory of Basic Pharmacology of Ministry of Education, Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, Guizhou 563006, China.
Shuangnian XuDepartment of Hematology, Southwest Hospital, Army Medical University, Chongqing 400038, China.
Ning GaoCollege of Pharmacy, Army Medical University, 30 Gaotanyan Street, Shapingba District, Chongqing 400038, China.
Army Medical University · CNSouthwest Hospital · CNZunyi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

1-Phosphatidylinositol 4-KinaseLeukemiaAMP-Activated Protein KinasesAnimalsCell Line, TumorDrug Resistance, NeoplasmHumansMice1-Phosphatidylinositol 4-KinaseAMP-Activated Protein KinaseschemoresistanceERK/AMPK/OXPHOS axisLeukemiaPI4KA

Identifiers

PMID36276647
PMCPMC9576605
OpenAlexW4307232082

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.