ReviewJournal of mid-life health
Xerostomia - A Comprehensive Review with a Focus on Mid-Life Health.
Review in Journal of mid-life health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 27 citations in OpenAlex.
- Oral Health Across the Menopausal Transition: Biological Pathways, Clinical Implications, and Future Perspectives.Journal of clinical medicine · 2026Review
- A Pilot Study Assessing the Oral Microbiome in Women of Menopausal Age: Do Oral Nitrate-Reducing Bacteria Play a Role?International dental journal · 2026Observational
- Salivary cortisol as a neuroendocrine stress biomarker for xerostomia in multiple sclerosis patients: a comparative cross-sectional study.BMC oral health · 2026Article
- Sex-Specific Oral Health: A Narrative Review of Hormonal Influences and Disease Patterns.Dentistry journal · 2026Review
- Exploring Beverage Intake and Dietary Timing Patterns in Medication-Induced Xerostomia: A Cross-Sectional Pilot Study.Nutrients · 2026Article
- Oral Side Effects of the Most Commonly Prescribed Drugs in Germany.Dentistry journal · 2026Article
- Xerostomia as an oral-systemic indicator: Etiology, diagnostic strategies and multimodal management approaches.Bioinformation · 2026Article
- Impact of hormonal phases on salivary characteristics and oral hygiene in women: a cross-sectional comparative study.BMC oral health · 2025Article
- Salivary Proteome Profile of Xerostomic Patients Reveals Pathway Dysregulation Related to Neurodegenerative Diseases: A Pilot Study.International journal of molecular sciences · 2025Article
- Oral Manifestations in Menopause-A Scoping Review.Medicina (Kaunas, Lithuania) · 2025Article
- Efficacy of Cevimeline on Xerostomia in Sjögren's Syndrome Patients: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.Current therapeutic research, clinical and experimental · 2025Review
- TGFβ2-Driven Ferritin Degradation and Subsequent Ferroptosis Underlie Salivary Gland Dysfunction in Postmenopausal Conditions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Oral complications during the two waves of COVID-19 pandemic in China: a prospective cross-section analysis of 510 cases using questionnaire.BMC oral health · 2024Article
- Prediction of xerostomia in elderly based on clinical characteristics and salivary flow rate with machine learning.Scientific reports · 2024Article
- Menopause and Oral Health: Clinical Implications and Preventive Strategies.Journal of mid-life healthReview
- Salivary Calcium and Albumin as Biomarkers of Oral Dryness in Postmenopausal Women: A Case-Control Analysis.Journal of International Society of Preventive & Community DentistryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Xerostomia is defined as the subjective complaint of a dry mouth. Xerostomia is common in menopausal women owing to the hormonal changes which take place during midlife. Studies show a higher incidence of oral cancer in the postmenopausal period which substantiates the theory of estrogen deficiency in carcinogenesis. Radiotherapy in the treatment of these cancers can lead to oral dryness. Other etiological factors of xerostomia include systemic diseases commonly occurring in middle-aged individuals and xerogenic drugs. Saliva plays a pivotal role in the maintenance of oropharyngeal health and xerostomia can severely impair the quality of life. The aim of this review was to provide vital information pertaining to the etiology, signs, diagnosis, and treatment of xerostomia with an emphasis on midlife health. The articles for this review were obtained from PubMed Central, Google Scholar, EBSCO, Science Direct, Medknow, Scopus, EMBASE, Web of Science, and authorized textbooks published between 1988 and 2021.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.