Evidence map›Paper›PMID 36276617›Full record

ArticleJournal of mid-life health

Salivary Menopausal Markers and Oral Health Status - A Hidden Hook Up.

B Soundarya, F Massillamani, S Kailasam, G Jayashree, N Narmadha, N Sornaa

Open access · diamondAbstract read
In one paragraph

Article in Journal of mid-life health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Oral Manifestations in Menopause-A Scoping Review.Medicina (Kaunas, Lithuania) · 2025
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

B SoundaryaDepartment of Oral Medicine and Radiology, Ragas Dental College and Hospital, Chennai, Tamil Nadu, India.
F MassillamaniDepartment of Oral Medicine and Radiology, Ragas Dental College and Hospital, Chennai, Tamil Nadu, India.
S KailasamDepartment of Oral Medicine and Radiology, Ragas Dental College and Hospital, Chennai, Tamil Nadu, India.
G JayashreeDepartment of Oral Medicine and Radiology, Ragas Dental College and Hospital, Chennai, Tamil Nadu, India.
N NarmadhaDepartment of Oral Medicine and Radiology, Ragas Dental College and Hospital, Chennai, Tamil Nadu, India.
N SornaaDepartment of Oral Medicine and Radiology, Ragas Dental College and Hospital, Chennai, Tamil Nadu, India.
Ragas Dental College & Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim and Objectives: The aim of our study was to evaluate salivary estradiol and salivary calcium in postmenopausal women with varying degrees of oral dryness. The primary objective was to establish the interrelationship between salivary parameters and oral health status among menopausal women and compare the same with premenopausal women and normal controls. Materials and Methods: The study included 60 women Group I consisted of healthy menstruating women between 25 and 34 years of age. In Group II premenopausal women between 35 and 45 years of age were present and Group III consisted of menopausal women between 45 and 60 years of age. Unstimulated saliva was collected from the participants and estradiol analysis was done using ELISA method and calcium analysis was done using Arsenazo III reaction using colorimetric method. The oral health status in these patients was determined by using xerostomia score, Russell's periodontal score, and oral hygiene index. The values obtained were subjected to statistical analysis and the results were derived. Results: On oral examination, most of them had poor oral hygiene, periodontal disease, and moderate to severe levels of xerostomia. Salivary estradiol levels were low and salivary calcium levels were high among postmenopausal women and as salivary estradiol levels decreased there was an increase in xerostomia scores and salivary calcium. And also as salivary calcium levels increased the periodontal disease scores increased. All parameters were within normal limits among healthy menstruating women. Conclusion: Saliva can be a preferred medium and an emerging alternative for serum to estimate estradiol and calcium levels. As a dentist, we have to educate them about the oral changes they will experience during menopause and emphasize its strong association between low estradiol levels. Oral hygiene instructions should be given for the maintenance of healthy periodontium. Menopausal women who experience severe postmenopausal symptoms can be identified and the dentist and gynecologist can work hand in hand to treat the symptoms of these women.

Indexed as

Menopauseoral hygieneperiodontitissalivary calciumsalivary estradiolxerostomia

Identifiers

PMID36276617
PMCPMC9583370
OpenAlexW4307227104

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.