Evidence map›Paper›PMID 36276369›Full record

ArticleFrontiers in public health2022

Walking and taking vitamin C alleviates oxidative stress and inflammation in overweight students, even in the short-term.

Qian Zhang, Miao Guo, Tianyi Chen, Huizhi Cheng, Qianwen Yang, Zhuohui Zhao, Rong She, Xiaoyan Yang, Wen Xiao, Xu Yang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Qian ZhangInstitute of Natural Antioxidants and Antioxidant Inflammation, Dali University, Dali, China.
Miao GuoJoint International Research Laboratory of Green Buildings and Built Environments (Ministry of Education), Chongqing University, Chongqing, China.
Tianyi ChenDepartment of Environmental Health, School of Public Health, Fudan University, Shanghai, China.
Huizhi ChengSchool of Public Health, Dali University, Dali, China.
Qianwen YangSchool of Public Health, Dali University, Dali, China.
Zhuohui ZhaoDepartment of Environmental Health, School of Public Health, Fudan University, Shanghai, China.
Rong SheInstitute of Natural Antioxidants and Antioxidant Inflammation, Dali University, Dali, China.
Xiaoyan YangInstitute of Natural Antioxidants and Antioxidant Inflammation, Dali University, Dali, China.
Wen XiaoInstitute of Eastern-Himalaya Biodiversity Research, Dali University, Dali, China.
Xu YangInstitute of Natural Antioxidants and Antioxidant Inflammation, Dali University, Dali, China.
Lijuan LiInstitute of Natural Antioxidants and Antioxidant Inflammation, Dali University, Dali, China.
Dali University · CNHubei University of Science and Technology · CNFudan University · CNChongqing University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Obese or overweight is a risk factor for some chronic diseases, and oxidative stress and inflammation may be one of the molecular mechanisms leading to the persistence of these chronic diseases. Discovering interventions to alleviate oxidative stress and inflammation in the overweight/obese population, is very important for public health and health education. Methods: A two-week panel intervention study (Run 0-Run 1-Run 2) was conducted. The subjects were 77 overweight/obese undergraduates attending Dali University, with a BMI>24 kg/m Results: The results demonstrated (1) Walking significantly alleviated ROS levels, and this was consistent in Run 1 and Run 2; (2) During Run1, all three intervention modes reduced levels of 8-OHdG, but there was a statistically insignificant increase during Run 2; (3) No alleviating effects of the three intervention modes on TNF-α levels during Run 1 and Run 2 were observed; (4) The alleviating effects of the three intervention modes on IL-1β levels during Run 1 and Run 2 were clear. Conclusion: Walking and taking vitamin C can reduce levels of ROS, 8-OHdG and IL-1β, but not TNF-α, in overweight/obese participants. These interventions may become potential preventive measures for the overweight against obese-induced oxidative stress and inflammation.

Indexed as

Ascorbic AcidOverweightHumansInflammationObesityOxidative StressReactive Oxygen SpeciesStudentsTumor Necrosis Factor-alphaWalkingAscorbic AcidReactive Oxygen SpeciesTumor Necrosis Factor-alphaalleviationinflammatory cytokineinterventionoverweight/obesityoxidative stresspanel studyvitamin Cwalking

Identifiers

PMID36276369
PMCPMC9581260
OpenAlexW4301430606

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.