Evidence map›Paper›PMID 36276292›Full record

ArticleJournal of oncology2022

Dynamic Predictive Models with Visualized Machine Learning for Assessing the Risk of Lung Metastasis in Kidney Cancer Patients.

Chan Xu, Qian Zhou, Wencai Liu, Wenle Li, Shengtao Dong, Wanying Li, Xiaofeng Xu, Ximin Qiao, Youli Jiang, Jingfang Chen and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 2 countries.

Chan XuClinical Medical Research Center, Xianyang Central Hospital, Xianyang, China.
Qian ZhouDepartment of Respiratory and Critical Care Medicine, The First People's Hospital of Chong Qing Liang Jiang New Area, Chongqing, China.
Wencai LiuDepartment of Orthopaedic Surgery, The First Affiliated Hospital of Nanchang University, Nanchang, China.ORCID https://orcid.org/0000-0002-5350-3125
Wenle LiXiamen University, Molecular Imaging and Translational Medicine Research Center, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, Xiamen, China.ORCID https://orcid.org/0000-0002-2933-646X
Shengtao DongDepartment of Spine Surgery, Second Affiliated Hospital of Dalian Medical University, Dalian 116000, China.ORCID https://orcid.org/0000-0002-5761-026X
Wanying LiClinical Medical Research Center, Xianyang Central Hospital, Xianyang, China.
Xiaofeng XuClinical Medical Research Center, Xianyang Central Hospital, Xianyang, China.
Ximin QiaoClinical Medical Research Center, Xianyang Central Hospital, Xianyang, China.
Youli JiangHengyang Medical School, School of Nursing, University of South China, Hengyang, Hunan, China.ORCID https://orcid.org/0000-0002-6856-5177
Jingfang ChenHengyang Medical School, School of Nursing, University of South China, Hengyang, Hunan, China.ORCID https://orcid.org/0000-0001-8389-7703
Chengliang YinFaculty of Medicine, Macau University of Science and Technology, Macau, China.ORCID https://orcid.org/0000-0001-8262-5749
Xian Yang Central Hospital · CNXiamen University · CNDalian Medical University · CNFirst People's Hospital of Chongqing · CNMacau University of Science and Technology · MONanchang University · CNShenzhen Third People’s Hospital · CNUniversity of South China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To establish and verify the clinical prediction model of lung metastasis in renal cancer patients. Method: Kidney cancer patients from January 1, 2010, to December 31, 2017, in the SEER database were enrolled in this study. In the first section, LASSO method was adopted to select variables. Independent influencing factors were identified after multivariate logistic regression analysis. In the second section, machine learning (ML) algorithms were implemented to establish models and 10-foldcross-validation was used to train the models. Finally, receiver operating characteristic curves, probability density functions, and clinical utility curve were applied to estimate model's performance. The final model was shown by a website calculator. Result: Lung metastasis was confirmed in 7.43% (3171 out of 42650) of study population. In multivariate logistic regression, bone metastasis, brain metastasis, grade, liver metastasis, N stage, Conclusion: This study provided preliminary evidence that the ML algorithm can be used to predict lung metastases in patients with kidney cancer. This low cost, noninvasive and easy to implement diagnostic method is useful for clinical work. Of course this model still needs to undergo more real-world validation.

Identifiers

PMID36276292
PMCPMC9586755
OpenAlexW4306249342

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.