Evidence map›Paper›PMID 36275847›Full record

SynthesisFrontiers in neural circuits2022

GABA

Massimo Avoli, Marco de Curtis, Maxime Lévesque, Laura Librizzi, Laura Uva, Siyan Wang

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in neural circuits, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Massimo AvoliMontreal Neurological Institute-Hospital, Montreal, QC, Canada.
Marco de CurtisEpilepsy Unit, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Istituto Neurologico Carlo Besta, Milan, Italy.
Maxime LévesqueMontreal Neurological Institute-Hospital, Montreal, QC, Canada.
Laura LibrizziEpilepsy Unit, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Istituto Neurologico Carlo Besta, Milan, Italy.
Laura UvaEpilepsy Unit, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Istituto Neurologico Carlo Besta, Milan, Italy.
Siyan WangMontreal Neurological Institute-Hospital, Montreal, QC, Canada.
Istituti di Ricovero e Cura a Carattere Scientifico · ITMontreal Neurological Institute and Hospital · CAFondazione IRCCS Istituto Neurologico Carlo Besta · ITMcGill University · CA

Funding

CIHR MOP130328CIHR PJT153310CIHR PJT166178
6 · The paper itself

Abstract

Under physiological conditions, neuronal network synchronization leads to different oscillatory EEG patterns that are associated with specific behavioral and cognitive functions. Excessive synchronization can, however, lead to focal or generalized epileptiform activities. It is indeed well established that in both epileptic patients and animal models, focal epileptiform EEG patterns are characterized by interictal and ictal (seizure) discharges. Over the last three decades, employing

Indexed as

Epilepsies, PartialEpilepsyEpilepsy, Temporal LobeAnimalsElectroencephalographygamma-Aminobutyric AcidSeizuresgamma-Aminobutyric Acidepileptiform synchronizationexcitatory transmissionGABAA receptorinhibitory transmissioninterictal spikesmesial temporal lobe epilepsyseizures

Identifiers

PMID36275847
PMCPMC9581276
OpenAlexW4301585429

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.