Evidence map›Paper›PMID 36275758›Full record

ReviewFrontiers in immunology2022

Immune and inflammatory mechanisms of abdominal aortic aneurysm.

Ana Cristina Márquez-Sánchez, Ekaterina K Koltsova

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers.

0numbers the graph read from it
0cells of the map it votes in
88citing papers in PubMed
15.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

88 citing papers in PubMed, 119 citations in OpenAlex.

  1. Article
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  6. Review
  7. Protectin D1/GPR37 Signaling Enhances Macrophage-Dependent Efferocytosis to Attenuate Experimental Abdominal Aortic Aneurysm Formation.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  8. Article
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  12. Review
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  19. Article
  20. Efferocytosis-associated Mrc1Frontiers in immunology · 2026
    Article

28 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ana Cristina Márquez-SánchezDepartment of Medicine, Department of Biomedical Sciences, Research Division in Immunology, Cedars-Sinai Cancer Institute, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Ekaterina K KoltsovaDepartment of Medicine, Department of Biomedical Sciences, Research Division in Immunology, Cedars-Sinai Cancer Institute, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Cedars-Sinai Medical Center · US

Funding

IL-27R signaling as a negative regulator of innate and adaptive anti-cancer immunity in hepatocellular carcinomaR01CA273925 · NCI · CEDARS-SINAI MEDICAL CENTER · PI KOLTSOVA, EKATERINA · 2022 to 2025
$3.3M
The unexpected role of IL-23 cytokine in atherosclerosisR01HL133669 · NHLBI · RESEARCH INST OF FOX CHASE CAN CTR · PI KOLTSOVA, EKATERINA · 2017 to 2020
$2.1M
Cytokine mediated regulation of stress myelopoiesis in abdominal aortic aneurysmR01HL149946 · NHLBI · RESEARCH INST OF FOX CHASE CAN CTR · PI KOLTSOVA, EKATERINA · 2020 to 2023
$2.1M
NCI NIH HHS R01 CA273925NHLBI NIH HHS R01 HL133669NHLBI NIH HHS R01 HL149946
6 · The paper itself

Abstract

Abdominal aortic aneurysm (AAA) is a life-threatening cardiovascular disease. Immune-mediated infiltration and a destruction of the aortic wall during AAA development plays significant role in the pathogenesis of this disease. While various immune cells had been found in AAA, the mechanisms of their activation and function are still far from being understood. A better understanding of mechanisms regulating the development of aberrant immune cell activation in AAA is essential for the development of novel preventive and therapeutic approaches. In this review we summarize current knowledge about the role of immune cells in AAA and discuss how pathogenic immune cell activation is regulated in this disease.

Indexed as

Aortic Aneurysm, AbdominalAnimalsDisease Models, AnimalMiceMice, Inbred C57BLabdominal aortic aneurysmcytokinesimmune cellsinflammationmicrobiotatissue microenvironmentvascular immunology

Identifiers

PMID36275758
PMCPMC9583679
OpenAlexW4301585088

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.