Evidence map›Paper›PMID 36275645›Full record

ArticleFrontiers in immunology2022

Costimulators expressed on human endothelial cells modulate antigen-dependent recruitment of circulating T lymphocytes.

Thomas D Manes, Vivian Wang, Jordan S Pober

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. The Transplant Bellwether: Endothelial Cells in Antibody-Mediated Rejection.Journal of immunology (Baltimore, Md. : 1950) · 2023
    Review
  8. Transendothelial Migration of Human B Cells: Chemokine versus Antigen.Journal of immunology (Baltimore, Md. : 1950) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Thomas D ManesDepartment of Immunobiology, Yale School of Medicine, New Haven, CT, United States.
Vivian WangDepartment of Immunobiology, Yale School of Medicine, New Haven, CT, United States.
Jordan S PoberDepartment of Immunobiology, Yale School of Medicine, New Haven, CT, United States.
Yale University · US

Funding

Human B cell infiltration into allografts: mechanisms and moleculesR21AI154187 · NIAID · YALE UNIVERSITY · PI MANES, THOMAS DAVID, POBER, JORDAN S · 2020 to 2021
$461k
NIAID NIH HHS R21 AI154187
6 · The paper itself

Abstract

Endothelial cells (ECs) can present antigens to circulating effector memory T cells (T

Indexed as

CD28 AntigensEndothelial CellsCD58 AntigensHumansImmunologic MemoryInterleukin-2Receptors, Antigen, T-CellSuperantigensCD28 AntigensCD58 AntigensInterleukin-2Receptors, Antigen, T-CellSuperantigenscostimulating moleculescytokine expressionflow chamber assayT celltransendothelial and transepithelial migration

Identifiers

PMID36275645
PMCPMC9582530
OpenAlexW4302305057

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.