Evidence map›Paper›PMID 36275361›Full record

Article3 Biotech2022

Dextran sodium sulfate alters antioxidant status in the gut affecting the survival of

Nishal Keshav, Ramyalakshmi Ammankallu, Shashidhar, Jagdish Gopal Paithankar, Manjeshwar Shrinath Baliga, Rajashekhar K Patil, Avinash Kundadka Kudva, Shamprasad Varija Raghu

Open access · greenAbstract read
In one paragraph

Article in 3 Biotech, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Frontiers in pharmacology · 2026
    Article
  3. Article
  4. Article
  5. Anti-Inflammatory Effects ofPreventive nutrition and food science · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. International journal of molecular sciences · 2024
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Nishal Keshav *Neurogenetics Laboratory, Department of Applied Zoology, Mangalore University, Mangalagangothri, 574199 Karnataka India.
Ramyalakshmi Ammankallu *Neurogenetics Laboratory, Department of Applied Zoology, Mangalore University, Mangalagangothri, 574199 Karnataka India.
Shashidhar *Neurogenetics Laboratory, Department of Applied Zoology, Mangalore University, Mangalagangothri, 574199 Karnataka India.
Jagdish Gopal PaithankarNitte University Center for Science Education and Research (NUCSER), Nitte (Deemed to be University), Mangalore, 575018 India.
Manjeshwar Shrinath BaligaMangalore Institute of Oncology, Mangalore, 575002 Karnataka India.
Rajashekhar K PatilNeurogenetics Laboratory, Department of Applied Zoology, Mangalore University, Mangalagangothri, 574199 Karnataka India.
Avinash Kundadka KudvaDepartment of Biochemistry, Mangalore University, Mangalagangothri, 574199 Karnataka India.
Shamprasad Varija RaghuNeurogenetics Laboratory, Department of Applied Zoology, Mangalore University, Mangalagangothri, 574199 Karnataka India.ORCID 0000-0001-5537-1405
Mangalore University · INMangalore Institute of Oncology · INNitte University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory bowel disease (IBD) is a group of disorders characterized by chronic inflammation in the intestine. Several studies confirmed that oxidative stress induced by an enormous amount of reactive free radicals triggers the onset of IBD. Currently, there is an increasing trend in the global incidence of IBD and it is coupled with a lack of adequate long-term therapeutic options. At the same time, progress in research to understand the pathogenesis of IBD has been hampered due to the absence of adequate animal models. Currently, the toxic chemical Dextran Sulfate Sodium (DSS) induced gut inflammation in rodents is widely perceived as a good model of experimental colitis or IBD. Supplementary Information: The online version contains supplementary material available at 10.1007/s13205-022-03349-2.

Indexed as

AntioxidantDextran sodium sulfateDrosophilaInflammatory bowel diseaseSmurfing

Identifiers

PMID36275361
PMCPMC9481858
OpenAlexW4296193646

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.