Evidence map›Paper›PMID 36275171›Full record

ArticleRSC advances2022

Large-scale synthesis of Notum inhibitor 1-(2,4-dichloro-3-(trifluoromethyl)-phenyl)-1

Benjamin N Atkinson, Nicky J Willis, Jennifer Smith, Rebecca Gill, Jody Ali, Zhou Xu, Ping-Shan Lai, Paul V Fish

Abstract read
In one paragraph

Article in RSC advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Benjamin N AtkinsonAlzheimer's Research UK UCL Drug Discovery Institute, University College London Cruciform Building, Gower Street London WC1E 6BT UK p.fish@ucl.ac.uk +44 (0)20 7679 6971.ORCID https://orcid.org/0000-0001-5511-9859
Nicky J WillisAlzheimer's Research UK UCL Drug Discovery Institute, University College London Cruciform Building, Gower Street London WC1E 6BT UK p.fish@ucl.ac.uk +44 (0)20 7679 6971.ORCID https://orcid.org/0000-0003-3245-5280
Jennifer SmithKey Organics Ltd Highfield Road Industrial Estate, Camelford Cornwall PL32 9RA UK.
Rebecca GillKey Organics Ltd Highfield Road Industrial Estate, Camelford Cornwall PL32 9RA UK.
Jody AliKey Organics Ltd Highfield Road Industrial Estate, Camelford Cornwall PL32 9RA UK.
Zhou XuWuXi AppTec (Tianjin) Co., Ltd. 168 Nanhai Road, 10th Avenue, Tianjin Economic-Technological Development Area (TEDA) Tianjin 300457 P.R. China.
Ping-Shan LaiWuXi AppTec (Tianjin) Co., Ltd. 168 Nanhai Road, 10th Avenue, Tianjin Economic-Technological Development Area (TEDA) Tianjin 300457 P.R. China.
Paul V FishAlzheimer's Research UK UCL Drug Discovery Institute, University College London Cruciform Building, Gower Street London WC1E 6BT UK p.fish@ucl.ac.uk +44 (0)20 7679 6971.ORCID https://orcid.org/0000-0002-2117-2173

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

1-Phenyl-1

Identifiers

PMID36275171
PMCPMC9478995

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.