Evidence map›Paper›PMID 36275136›Full record

ArticleJournal of radiosurgery and SBRT2022

Dosimetric impact of tumor position displacements between photon and proton stereotactic body radiation therapy for lung cancer.

Liu Chieh-Wen, Ma Tianjun, Gray Tara, Ahmed Saeed, Yu Naichang, Stephans Kevin L, Videtic Gregory M M, Xia Ping

Open access · greenAbstract read
In one paragraph

Article in Journal of radiosurgery and SBRT, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Liu Chieh-WenDepartment of Radiation Oncology, Cleveland Clinic, 9500 Euclid Ave., Cleveland, OH 44195, USA.
Ma TianjunDepartment of Radiation Medicine, MedStar Georgetown University Hospital, 3800 Reservoir Rd NW, Washington, DC 20007, USA.
Gray TaraDepartment of Radiation Oncology, Cleveland Clinic, 9500 Euclid Ave., Cleveland, OH 44195, USA.
Ahmed SaeedDepartment of Radiation Oncology, Cleveland Clinic, 9500 Euclid Ave., Cleveland, OH 44195, USA.
Yu NaichangDepartment of Radiation Oncology, Cleveland Clinic, 9500 Euclid Ave., Cleveland, OH 44195, USA.
Stephans Kevin LDepartment of Radiation Oncology, Cleveland Clinic, 9500 Euclid Ave., Cleveland, OH 44195, USA.
Videtic Gregory M MDepartment of Radiation Oncology, Cleveland Clinic, 9500 Euclid Ave., Cleveland, OH 44195, USA.
Xia PingDepartment of Radiation Oncology, Cleveland Clinic, 9500 Euclid Ave., Cleveland, OH 44195, USA.
Cleveland Clinic · USGeorgetown University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To investigate the impact of tumor position displacements (TPDs) on tumor dose coverage in photon and proton stereotactic body radiation therapy (SBRT) treatments for lung cancer patients. Methods: From our institutional database of 2877 fractions from 770 lung cancer patients treated with photon SBRT in 2017-2021, 163 fractions from 88 patients with recorded iso-center shifts of >1.5 cm in any direction under kV-cone-beam CT guidance were identified. By double registrations with bony and tumor alignments, the difference between the iso-center shifts of these two alignments was categorized as TPDs. One fraction from each of 15 patients who had TPD magnitudes >3 mm were selected for this study. For each patient, one proton plan using intensity modulated proton therapy (IMPT) with robust optimization was generated retrospectively. All photon plans had V Results: The range of magnitude of TPDs was 3.58-28.71 mm. In photon plans, TPDs did not impact tumor dose coverage, still achieving V Conclusions: Adequate tumor dose coverage was achieved in photon SBRT for magnitude of TPDs up to 20 mm. TPDs had greater impact in proton SBRT and adaptive planning was needed when the magnitude of TPDs>10 mm to provide adequate tumor dose coverage.

Indexed as

adaptive radiotherapyanatomical changeIMPTprotonSBRTtumor position displacement

Identifiers

PMID36275136
PMCPMC9489077
OpenAlexW4307232500

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.